创建医院社区一体化"金字塔"肝癌筛查模式,实现肝癌早筛早诊早治  

Establishing an integrated hospital-community pyramid for screening and achieving hepatocellular carcinoma early diagnosis and treatment

作　　者：郝新 樊蓉[1] 郭亚兵[1,2] 侯金林 Hao Xin;Fan Rong;Guo Yabing;Hou Jinlin(Department of Infectious Diseases,Nanfang Hospital,Southern Medical University,State Key Laboratory of Organ Failure Research,Guangdong Provincial Key Laboratory of Viral Hepatitis Research,Guangzhou 510515,China;Shenzhen Hospital,Southern Medical University,Shenzhen 518110,China)

机构地区：[1]南方医科大学南方医院感染内科,器官衰竭研究国家重点实验室,广东省病毒性肝炎研究重点实验室,广州510515 [2]南方医科大学深圳医院,深圳518110

出　　处：《中华肝脏病杂志》2021年第4期289-292,共4页Chinese Journal of Hepatology

基　　金：深圳市医药卫生"三名工程"高层次医学团队项目(SZSM201911001)。

摘　　要：肝细胞癌(HCC)的综合管理是一个全程、动态和个体化的过程。如何科学地确定肝癌高危/极高危人群、制定分层的监测方案,是早发现、早诊断和提高HCC总体生存率的关键环节。基于HCC风险预测模型、极早期预警标志物和早期筛查工具,精准识别高危/极高危人群,并将其运用于医院和社区筛查,构建医院社区一体化的"金字塔"HCC筛查模式,对HCC高危人群及患者实行跨学科科学管理和治疗,最终降低肝癌相关死亡率。The comprehensive management of hepatocellular carcinoma(HCC)is a complete,dynamic and personalized process.Therefore,how to scientifically determine the HCC high-risk/extremely high-risk populations and develop a stratified monitoring plan is the key link to early detection,diagnosis and improvement of overall survival.In addition,accurately identifying high-risk/extremely high-risk groups based on the HCC risk prediction model,and applying it to establish an integrated hospital-community pyramid for HCC screening through the implementation of interdisciplinary scientific management and treatment may ultimately reduce HCC-related mortality rate.

关 键 词：肝细胞癌 早期筛查 综合治疗 aMAP肝癌风险评分 医院社区一体化 

分 类 号：R735.7[医药卫生—肿瘤]