华北油田职工结直肠腺瘤性息肉与Hp感染Logistic回归分析  

Logistic regression analysis of colorectal adenomatous polyps and Helicobacter pylori infection among employees in Huabei Oilfield

作　　者：刘复娜[1] 董云峰 刘小娟[1] 陈策[1] 郭凤霞[1] 张红丽 刘江奎[1] LIU Funa;DONG Yunfeng;LIU Xiaojuan;CHEN Ce;GUO Fengxia;ZHANG Hongli;LIU Jiangkui(Department of Gastroenterology,General Hospital of North China Petroleum Administration,Renqiu,062550,China)

机构地区：[1]华北石油管理局总医院消化内科,河北任丘062550

出　　处：《中国中西医结合消化杂志》2021年第4期263-266,271,共5页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：河北省卫健委课题(No:20191167)。

摘　　要：目的::探讨华北油田职工结直肠腺瘤性息肉与Hp感染Logistic回归分析。方法:选择2017年1月—2018年12月来体检结肠镜的油田职工1000例,根据检查结果将156例结直肠腺瘤性息肉患者设为息肉组,在844例无明显异常工人中选择156例设为对照组;对2组受试人员一般资料进行对比分析,对2组息肉数目、大小、部位、Hp感染情况以及TG、TC、LDL-C进行对比,并对差异明显的项目进行Logistic回归分析。结果:息肉组Hp阳性感染率62.82%显著高于对照组40.64%(P<0.05);不同年龄、息肉数目的息肉组患者Hp感染阳性率比较,差异有统计学意义(P<0.05);2组Hp感染阳性者TC、TG、LDL-C血脂相关指标均高于Hp阴性者(P<0.05);以结直肠腺瘤性息肉为应变量,以Hp感染阳性、年龄、息肉数目、TC、TG、LDL-C为自变量进行单因素分析显示所有指标均为危险因素;以结直肠腺瘤性息肉为应变量,以单因素分析中差异显著的指标为自变量,构建多因素Logistic回归模型,结果显示,Hp感染阳性、年龄差异有统计学意义(P<0.05)。结论:本研究中年龄、Hp感染均可作为腺瘤性息肉独立危险因素,但本研究对象为华北油田职工,因此在正常人群中Hp感染是否可作为腺瘤性息肉的独立危险因素还需更多基础类研究进行验证。Objective:Objective:To explore Logistic regression analysis of colorectal adenomatous polyps and Helicobacter pylori infection among employees in Huabei Oilfield.Methods:1000 oilfield workers who came to our hospital for medical examination of colonoscopy from 2017.01.01 to 2018.12.31 were selected.According to the examination results,156 patients with colorectal adenomatous polyps were divided into polyp group and 156 of 844 normal workers were selected as control group.Compare and analyze the general data age,height and weight of the two groups of subjects,compare the number,size,location,Hp infection of the two groups and TG,TC,LDL-C,and analyze the items with statistical differences Logistic regression analysis was performed.Results:The positive infection rate in the polyp group was 62.82%,which was significantly higher than that in the control group(40.38%)(P<0.05).Compared with the general data of Hp infection rate in patients with rectal adenomatous polyps in the polyp group,the age and number of polyps were statistically different(P<0.05);TC,TG,LDL-C blood lipid related indexes of two groups of Hp-positive persons were higher than those of Hp-negative persons(P<0.05);rectal adenomatous polyps were used as dependent variables,and Hp infection positive,age,polyps The number,TC,TG,LDL-C were independent variables.Univariate Logistic regression analysis showed that all indicators were risk factors;rectal adenomatous polyps were the dependent variables,and the indicators with statistical differences in univariate Logistic regression analysis were Independent variables were used to construct a multi-factor Logistic regression model.The results showed that Hp infection was positive and the age was statistically different(P<0.05).Conclusion:In this study,age and Hp infection can be used as independent risk factors for adenomatous polyps,but this study is for employees in North China Oilfield.Therefore,whether Hp infection can be used as an independent risk factor for adenomatous polyps in the normal population Mo

关 键 词：结直肠腺瘤性息肉 HP LOGISTIC回归分析 

分 类 号：R573.6[医药卫生—消化系统]