加味清胰汤治疗急性胰腺炎的临床疗效分析  

Analysis of the clinical effect of Jiawei Qingyi decoction on acute pancreatitis

作　　者：明志祥[1] 许健华[1] 张若怡 MING Zhixiang;XU Jianhua;ZHANG Ruoyi(Department of General Surgery,Nantong Hospital of Traditional Chinese Medicine,Nantong,226001,China;Department of Encephalopathy,Nantong Hospital of Traditional Chinese Medicine)

机构地区：[1]南通市中医院中医外科,江苏南通226001 [2]南通市中医院脑病科

出　　处：《中国中西医结合消化杂志》2021年第4期284-287,共4页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：2019年度南通市市级科技计划(指导性)项目(No:MSZ19056)。

摘　　要：目的:观察加味清胰汤治疗急性胰腺炎(AP)的临床疗效。方法:将AP患者79例随机分为对照组(32例)和观察组(47例)。对照组给予AP的常规治疗,观察组在对照组治疗基础上加用加味清胰汤(鼻饲)。比较2组患者用药2 d、4 d、7 d后血清炎性因子指标、指标转阴时间及AP相关症状改善时间。结果:与治疗前比较,治疗后2组患者血清炎性因子指标均下降(P<0.01),且治疗后观察组炎性因子总体水平低于对照组(P<0.01);治疗后观察组血清炎性因子转阴时间明显小于对照组(P<0.01)。2组AP相关症状均得以改善,观察组改善时间较对照组缩短(P<0.01)。对照组治愈率为78.13%,观察组治愈率为95.74%,观察组治愈率高于对照组(P<0.01)。结论:加味清胰汤治疗AP疗效显著,可以较显著减轻患者的炎症反应,更快改善AP患者的临床症状,从而改善预后。Objective:To observe the clinical effect of Jiawei Qingyi decoction on acute pancreatitis(AP).Methods:All patients with acute pancreatitis(79 cases)were randomly divided into control group(32 cases)and observation group(47 cases).The control group was given routine treatment,and the observation group was given Jiawei Qingyi decoction on the basis of the control group treatment.Serum inflammatory factor index,indicator turning negative time and AP related symptom improvement time were compared between the two groups after 2 days,4 days and 7 days.Results:After treatment and before treatment,the serum inflammatory factor index of both groups decreased(P<0.01),and the overall level of inflammatory factor after treatment in the observation group was lower than that in the control group(P<0.01).After treatment,the conversion time of inflammatory factors in the observation group was significantly shorter than that in the control group(P<0.01).AP related symptoms were improved in both groups,and the improvement time in the observation group was shorter than that in the control group(P<0.01).The cure rate was 78.13%in the control group and 95.74%in the observation group,which was higher than that in the control group(P<0.01).Conclusion:Jiawei Qingyi decoction has a significant effect in the treatment of acute pancreatitis,which can significantly reduce the inflammatory response in patients,improve the clinical symptoms of AP patients faster,and thus improve the prognosis.

关 键 词：急性胰腺炎 阳明腑实 腹痛 加味清胰汤 前瞻性研究 中医药 随机对照研究 

分 类 号：R576[医药卫生—消化系统]