浅析非酒精性脂肪性肝病从肠道论治  

Treatment of nonalcoholic fatty liver disease by adjusting the function of large intestine

作　　者：张晓星 刘延东[1] 杨川[1] 王萌嘉 ZHANG Xiaoxing;LIU Yandong;YANG Chuan

机构地区：[1]哈尔滨工业大学附属黑龙江省医院中西医结合科,哈尔滨150036

出　　处：《中国中西医结合消化杂志》2021年第4期294-298,共5页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：黑龙江省中医药科研项目(No:ZHY18-135)。

摘　　要：非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是目前全球及我国发病率最高的肝脏疾病,其发病机制尚不明确,亦缺乏疗效可靠的治疗手段及治疗药物。西医治疗存在治疗药物及作用机制单一、需多药物联合使用、治疗费用高、不良反应大、疾病易复发等问题,临床疗效有待商榷。NAFLD属中医"肝癖"范畴,中医治疗多从肝病治肝入手,虽可以根据具体病情辨证论治,因时因地因人制宜,但临床疗效仍不尽如人意。随着"肠-肝轴"理论的提出,医者开始转换思路,从肠道论治肝病成为目前的研究热点,这一观点也正好契合中医整体观的思想。现拟从中医角度出发,阐述肠道与肝脏在生理、病理上的相互联系,以柴胡汤剂为例分析古方中治疗肝病的思路,对NAFLD从肠论治进行理论探讨。Nonalcoholic fatty liver disease belongs to the category of "liver stasis" in traditional Chinese medicine, it involves a wide range of viscera, complicated pathological factors, and lack of unified diagnosis and treatment standards, which result in a variety of treatment methods but poor effect.This article starts with the theory of the connection between the liver and the large intestine, expounds the relationship between the liver and the large intestine in physiology and pathology, and puts forward that the treatment of nonalcoholic fatty liver disease should be based on the treatment of the intestine by analyzing the idea of treating liver disease in the classical formula, so as to provide new means and theoretical guidance for the treatment of the disease.

关 键 词：非酒精性脂肪性肝病 肝 大肠 肝与大肠相通 肠-肝轴 

分 类 号：R575.1[医药卫生—消化系统]