血液净化膜材料的临床发展  

Clinical development of blood purification membrane materials

作　　者：于茜[1] 周建辉[1] 赵小淋 谢大洋[1] 曹雪莹[1] Yu Qian;Zhou Jianhui;Zhao Xiaolin;Xie Dayang;Cao Xueying(Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing 100853, China)

机构地区：[1]解放军总医院第一医学中心肾脏病医学部,解放军肾脏病研究所,肾脏疾病国家重点实验室,国家慢性肾病临床医学研究中心,肾脏疾病研究北京市重点实验室,北京100853

出　　处：《中华肾病研究电子杂志》2021年第2期103-108,共6页Chinese Journal of Kidney Disease Investigation（Electronic Edition）

基　　金：国家重点研发计划课题(2016YFC1103004)。

摘　　要：血液净化技术在不断发展,影响透析质量很重要的一方面是透析器膜材料。膜材料以及制备工艺的探索,是临床血液净化技术发展的重要部分。本文介绍了血液净化膜材料的历史及临床需求,概括了目前主要发展方向:以增加大分子量毒素清除来改善终末期肾衰竭患者的临床结局、提高生物相容性、减少凝血,列举了多项新型膜材料及其优势。With the continuous development of blood purification technology,the membrane material of dialyzer is one of the most important factors affecting the quality of dialysis.The exploration of membrane materials and preparation technology is an important part of the development of clinical blood purification technology.This paper introduced the history and clinical requirements of blood purification membrane materials,and summarized the main development direction:to improve the clinical outcome of patients with end-stage renal failure by increasing the removal of toxins of large molecular weight,improve biocompatibility,and reduce coagulation.A number of new membrane materials and their advantages were listed.

关 键 词：膜材料 有效截留 生物相容性 高通量 

分 类 号：G63[文化科学—教育学]