甘油果糖不同输液方式对重度脑卒中患者的应用效果分析  

Effect analysis of different infusion methods of glycerol fructose in patients with severe stroke

作　　者：阎丽媚 张小倩[1] 陶东霞[1] YAN Li-mei;ZHANG Xiao-qian;TAO Dong-xia(Neurology Department,the First Affiliated Hospital of China Medical University,Shenyang 110001,China)

机构地区：[1]中国医科大学附属第一医院神经内科,辽宁沈阳110001

出　　处：《实用药物与临床》2021年第5期428-432,共5页Practical Pharmacy and Clinical Remedies

基　　金：国家自然科学基金(81801053);中国医科大学附属第一医院科研立项(HLB-2017-08)。

摘　　要：目的比较甘油果糖不同输液方式对重症脑卒中患者的应用效果。方法选取2017年7月至2019年3月于我院神经内科重症监护室住院的200例重症脑卒中患者,随机分为观察组与对照组,各100例。观察组予以甘油果糖中等长度导管置管输液,对照组予以甘油果糖静脉留置针输液。收集患者性别、年龄、留置时间、住院天数、并发症等临床资料,并进行相关的统计学分析。结果观察组的留置时间长于对照组,穿刺次数少于静脉留置针(P<0.05);观察组外渗、堵管、静脉炎发生率明显低于对照组,两组间差异具有统计学意义(P<0.05);两组间的感染和静脉血栓发生率差异无统计学意义(P>0.05)。Logistic回归分析显示,静脉置管方式是引起外渗(校正后OR=4.571,P=0.005)和堵管(校正后OR=16.466,P=0.015)的独立危险因素。经治疗,两组患者神经功能缺损CSS评分及日常生活能力BI评分均较治疗前有改善,其中CSS评分降低,BI评分升高(P<0.05);且观察组患者上述评分改善幅度均显著优于对照组,差异具有统计学意义(P<0.05)。结论与留置针输液相比较,甘油果糖中等长度导管置管输液能减少重症脑卒中患者静脉输液的并发症,减少外周血管损伤,减少穿刺次数,是更适合于神经重症患者的静脉输液方式。Objective To compare the effect of different infusion methods of glycerol fructose on patients with severe neurological stroke.Methods A total of 200 severe stroke patients who were hospitalized in the Intensive Care Unit of Neurology Department from July 2017 to March 2019 were selected and randomly divided into observation group and control group,with 100 cases in each group.Patients in the observation group were given glycerol fructose by medium-length catheter infusion,and patients in the control group were given glycerol fructose by indwelling needle infusion.The gender,age,indwelling time duration,hospitalization days,complications and other clinical data of the two groups of patients were collected and analyzed.Results The indwelling duration of observation group was longer than that of the control group,and the puncture times was less than that of the control group(P<0.05).The incidence rate of extravasation,blockage and phlebitis of observation group was significantly lower than those of the control group,and the difference between the two groups was statistical(P<0.05).There was no statistical difference in the incidence of infection or venous thrombosis between the two groups(P>0.05).Logistic regression analysis showed that the infusion methods was an independent risk factor for causing extravasation(after adjusment,OR=4.571,P=0.005)and blockage(after adjusment,OR=16.466,P=0.015).After treatment,CSS scores decreased and BI scores of daily living ability for neurological deficits in both groups were improved compared with those before treatment,with CSS scores decreased and BI scores increased(P<0.05).In addition,the improvement in the above scores in observation group was significantly better than that in control group(P<0.05).Conclusion For severe stroke patients,medium length catheter infusion can reduce the complications of intravenous infusion therapy,reduce the peripheral vascular injury and puncture times as compared with indwelling needle infusion,which is a more suitable intravenous infusion mo

关 键 词：甘油果糖 中等长度导管 静脉留置针 静脉输液并发症 重症脑卒中 

分 类 号：R743.3[医药卫生—神经病学与精神病学]