CO^(2)激光治疗喉癌前病变及早期声门型喉癌的疗效分析  

Efficacy of CO^(2) Laser in the Treatment of Precancerous Laryngeal Lesions and Early Glottic Laryngeal Cancer

作　　者：胡万青[1] 徐东亮[1] HU Wanqing;XU Dongliang(Department of Otorhinolaryngology,Ma’anshan People’s Hospital,Ma’anshan,Anhui,243000,China)

机构地区：[1]安徽马鞍山市人民医院耳鼻咽喉科,243000

出　　处：《中国中西医结合耳鼻咽喉科杂志》2021年第2期112-116,共5页Chinese Journal of Otorhinolaryngology in Integrative Medicine

摘　　要：目的探讨CO_(2)激光治疗喉癌前病变及早期声门型喉癌的临床效果。方法选取2014年1月~2019年9月在我科行支撑喉镜下CO_(2)激光显微手术治疗喉癌前病变及早期声门型喉癌患者30例(喉癌前病变20例,早期声门型喉癌10例),观察患者术后恢复情况。结果30例患者均完成手术,术中均未出现并发症。3例患者因病灶累及前联合,术后2个月出现声带粘连。术后随访6个月~3年。20例喉癌前病变患者中,1例成人声带乳头状瘤患者复发,再次给予CO^(2)激光手术后未再复发;1例声带白斑复发并癌变,行喉裂开术;其余18例治愈。10例早期声门型喉癌患者中1例切缘呈阳性,再次行CO^(2)激光手术治疗;1例复发再次行CO^(2)激光手术治疗;1例复发行喉部分切除术。结论CO^(2)激光可完整切除病灶,保留喉部功能,对于复发病例可进行补救治疗,是治疗喉癌前病变及早期声门型喉癌的有效方式。Objective To investigate the clinical effect of CO^(2) laser in the treatment of pre-laryngeal cancer and early glottic laryngeal cancer.Methods A total of 30 patients with pre-larynx precancerous lesions and early glottic laryngeal carcinoma underwent CO^(2) laser microsurgery under laryngoscope in our department from January 2014 to September 2019(20 patients with Laryngeal precancerous lesions and 10 patients with early glottic laryngeal cancer).The postoperative recovery of the patients was observed.Results All 30 patients completed the operation,and no complications occurred during the operation.Vocal cord adhesions occurred in 3 patients 2 months after surgery because of anterior union involvement.The follow-up period was 6 months to 3 years.Of the 20 patients with laryngeal precancerous lesions,one patient with adult vocal cord papilloma recurred and did not relapse after another CO^(2) laser surgery;one patient with vocal cord white spots recurred and became cancerous and underwent laryngectomy;the remaining 18 patients were cured.Among the 10 patients with early glottic laryngeal carcinoma,1 had a positive surgical margin and was again treated with CO^(2) laser surgery;1 had recurrence and received CO^(2) laser surgery again;1 had recurrence and had partial laryngectomy.Conclusions The CO^(2) laser can completely remove the lesion and retain the laryngeal function.It can be used for remedial treatment of recurrent cases.It is an effective way to treat laryngeal precancerous lesions and early glottic laryngeal cancer.

关 键 词：CO_(2)激光 喉癌前病变 早期声门型喉癌 

分 类 号：R739.65[医药卫生—肿瘤]