超声造影联合彩超检查在原发性肝癌、转移性肝癌中的鉴别诊断意义  

Significance of contrast-enhanced ultrasound combined with color ultrasound in the differential diagnosis of primary hepatic carcinoma and metastatic hepatic carcinoma

作　　者：毛楠 卢冠男[2] MAO Nan;LU Guan-nan(Department of Ultrasound,Tieling Central Hospital,Liaoning Province,Tieling 112000,China;Department of Respiratory Medicine,Affiliated Hospital of Jilin Medical College,Jilin Province,Jilin 132013,China)

机构地区：[1]辽宁省铁岭市中心医院超声科,辽宁铁岭112000 [2]吉林医药学院附属医院呼吸内科,吉林吉林132013

出　　处：《中国当代医药》2021年第15期155-158,共4页China Modern Medicine

基　　金：吉林省高等教育学会高教科研课题(JGJX2018 D155)。

摘　　要：目的探究超声造影(CEUS)联合彩超在原发性肝癌(PHC)、转移性肝癌(MHC)中的鉴别诊断意义。方法选取2018年6月~2019年10月铁岭市中心医院收治的92例肝癌患者作为研究对象,根据病因不同将其分为PHC组和MHC组,每组各46例。PHC组采用CEUS、彩超检查,MHC组检查方法同PHC组一致,比较两组CEUS、彩超及CEUS联合彩超的检出率,以及CEUS、彩超分别检查的血流灌注、血流血供情况。结果PHC组的峰值时间长于MHC组,增强强度高于MHC组,差异有统计学意义(P<0.05);MHC组的始增时间长于PHC组,增强速率、50%清除斜率高于PHC组,差异均有统计学意义(P<0.05)。PHC组的肝动脉最小流速、门静脉流速慢于MHC组,肝动脉峰值流速快于MHC组,差异有统计学意义(P<0.05);MHC组的肝动脉内径短于PHC组,肝动脉阻力指数低于PHC组,差异均有统计学意义(P<0.05)。CEUS联合彩超的检出率高于CEUS、彩超的检出率,差异有统计学意义(P<0.05)。结论CEUS联合彩超对PHC与MHC有更高的鉴别诊断价值,具有临床应用意义。Objective To investigate the significance of differential diagnosis of primary hepatic carcinoma(PHC)and metastatic hepatic carcinoma(MHC)by contrast-enhanced ultrasound(CEUS)combined with color ultrasound.Methods A total of 92 patients with liver cancer admitted to Tieling Central Hospital from June 2018 to October 2019 were selected as the research subjects.According to different etiology,they were divided into the PHC group and the MHC group,with 46 cases in each group.CEUS and color ultrasound were used in the PHC group,and the methods of examination in the MHC group were the same as those in the PHC group.The detection rates of CEUS,color ultrasound and CEUS combined with color ultrasound were compared between the two groups,as well as the blood perfusion and blood supply in the CEUS and color ultrasonography.Results The peak time of the PHC group was longer than that of the MHC group,and the enhancement intensity was higher than that of the MHC group,the differences were statistically significant(P<0.05);the initial increase time of the MHC group was longer than that of the PHC group,the enhancement rate and 50%clearance slope were higher than that of the PHC group,the differences were statistically significant(P<0.05).The flow velocity of hepatic artery in the PHC group was shorter than that in the MHC group,the difference was statistically significant(P<0.05).The detection rate of CEUS combined with CDUS was higher than that of CEUS and CDUS,the difference was statistically significant(P<0.05).Conclusion CEUS combined with color ultrasound can obtain higher differential diagnosis value for PHC and MHC,and has clinical application significance.

关 键 词：超声造影 多普勒彩超 原发性肝癌 转移性肝癌 诊断意义 

分 类 号：R73[医药卫生—肿瘤]