长非编码RNA在前列腺癌中的作用机制  

Mechanism of long non-coding RNA in prostate cancer

作　　者：张小飞 胡建鹏[1] 崔飞伦[1] Zhang Xiaofei;Hu Jianpeng;Cui Feilun(Department of Urology Surgery,Affiliated People′s Hospital of Jiangsu University,Zhenjiang 212002,China)

机构地区：[1]江苏大学附属人民医院泌尿外科,镇江212002

出　　处：《国际肿瘤学杂志》2021年第2期117-120,共4页Journal of International Oncology

基　　金：江苏省自然科学基金(BK20191221);江苏省社会发展重点病种规范化诊疗项目(BE2016715);江苏省青年医学重点人才项目(QNRC2016457);江苏省卫生和计划生育委员会基金项目(H2017089)。

摘　　要：长非编码RNA(lncRNA)是一类转录本长度超过200个核苷酸、不能编码蛋白质的RNA分子。近年的研究表明,在机体的生理和病理过程中,lncRNA发挥重要作用,参与前列腺癌的发生、发展和转移。深入研究lncRNA在前列腺癌中的作用机制,有望为前列腺癌的诊断及治疗提供新的思路。Long non-coding RNA(lncRNA)is a type of RNA molecule whose transcript is longer than 200 nucleotides and cannot encode protein.Studies in recent years have shown that lncRNA plays an important role in the physiological and pathological processes of the body.It participates in the occurrence,development and metastasis of prostate cancer.Further study on the role and mechanism of lncRNA in prostate cancer is expected to provide new ideas for the diagnosis and treatment of prostate cancer.

关 键 词：前列腺肿瘤 RNA 长链非编码 

分 类 号：R737.25[医药卫生—肿瘤]