原发性胃淋巴瘤临床病理特征及内镜诊断分析  

Clinicopathologic features and endoscopic presentations of primary gastric lymphoma

作　　者：崔建芳 王亚丹[1] 吴静[2] 王静 蔺武[1] 王沧海[1] 魏南[1] 郭春梅[1] CUI Jianfang;WANG Yadan;WU Jing;WANG Jing;LIN Wu;WANG Canghai;WEI Nan;GUO Chunmei(Department of Gastroenterology,the Affiliated Beijing Shijitan Hospital of Capital Medical University,Beijing 100038;Department of Gastroenterology,the Affiliated Beijing Friendship Hospital of Capital Medical University,China)

机构地区：[1]首都医科大学附属北京世纪坛医院消化内科,北京100038 [2]首都医科大学附属北京友谊医院消化内科

出　　处：《胃肠病学和肝病学杂志》2021年第5期567-570,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的分析原发性胃淋巴瘤(primary gastric lymphoma,PGL)及内镜下疑诊PGL患者的临床病理和内镜特征,提高PGL的诊断准确率。方法选取2010年12月至2018年12月在首都医科大学附属北京世纪坛医院消化内科明确诊断为PGL患者43例(病理确诊组)、病理否定PGL患者75例(病理否定组,病理诊断阴性15例、胃癌60例),回顾性分析其内镜及临床病理特征。结果腹痛是PGL、疑似PGL患者典型症状,分别占41.9%和32.0%,两组之间性别、年龄、临床症状差异无统计学意义(P>0.05)。病理确诊组内镜下表现:53.5%溃疡性病变,34.9%隆起性病变,11.6%浸润性生长病变。病理否定组内镜下表现:28.0%浸润性生长病变,37.3%溃疡性病变,34.7%隆起性病变,两组患者的内镜表现比较,差异有统计学意义(P<0.05)。病理类型以弥漫大B细胞淋巴瘤居多。结论PGL和疑诊PGL患者具有相似的临床症状,内镜表现均以溃疡性病变为主,虽然PGL的诊断率相对较低,但可以通过内窥镜进行鉴别。为了提高诊断准确率,应进行重复的内窥镜活检,并在未来开发新的内镜技术。Objective To improve diagnostic accuracy of primary gastric lymphoma(PGL)by analyzing clinicopathological and endoscopic features of PGL and suspected PGL.Methods Clinical and endoscopic records of 43 patients with PGL(PGL group)and 75 patients with suspected PGL(suspected PGL group)in Department of Gastroenterology,the Affiliated Beijing Shijitan Hospital of Capital Medical University were retrospectively analyzed.Results Abdominal pain was the predominant symptom in both the PGL group(41.9%)and suspected PGL group(32.0%).There was no significant difference in sex,age and clinical symptoms between the two groups(P>0.05).In the PGL group,53.5%were ulcerative lesions,34.9%were uplift-like lesions,11.6%were diffuse infiltrative changes.In the suspected PGL group,28.0%were diffuse infiltrative changes,37.3%were ulcerative lesions,34.7%were uplift-like lesions.There was significant difference between the two groups(P<0.05).Most of the pathological types were diffuse large B-cell lymphoma.Conclusion PGL and suspected PGL have similar clinical symptoms,and the endoscopic findings of them are mainly ulcerative lesions.Although the diagnostic rate of PGL is low,it can be distinguished by endoscopy.In order to improve the accuracy of diagnosis,repeated endoscopic biopsy should be performed and new endoscopic techniques should be developed in the future.

关 键 词：原发性胃淋巴瘤 临床病理特征 内镜表现 

分 类 号：R735.2[医药卫生—肿瘤]