肿瘤电场治疗在胶质母细胞瘤治疗中的应用进展  

Advances in application of tumor treating fields in glioblastoma

作　　者：许彦龙 李国强 余跃[1,2,3] 张祎年 XU Yanlong;LI Guoqiang;YU Yue;ZHANG Yinian(Department of Neurosurgery,Lanzhou University Second Hospital,Lanzhou 730030,China;the Second School of Clinical Medicine,Lanzhou University,Lanzhou 730030,China;Institute of Neurology,Lanzhou University,Lanzhou 730030,China)

机构地区：[1]兰州大学第二医院神经外科,甘肃兰州730030 [2]兰州大学第二临床医学院,甘肃兰州730030 [3]兰州大学神经病学研究所,甘肃兰州730030

出　　处：《中国医学物理学杂志》2021年第5期647-649,共3页Chinese Journal of Medical Physics

基　　金：国家自然科学基金(81771297)。

摘　　要：肿瘤电场治疗是一种新型的破坏肿瘤细胞有丝分裂的抗癌治疗方法,美国食品和药品管理局批准的第一个适应证是复发性胶质母细胞瘤,目前也已广泛应用于其他肿瘤的治疗。本文对肿瘤电场治疗的作用机制、治疗特点及其在胶质母细胞瘤治疗中的应用进展进行综述,分析其优点和不足,并对肿瘤电场治疗在胶质母细胞瘤治疗中的应用前景进行展望。Tumor treating fields(TTFields)is a novel anticancer treatment that disrupts tumor cell mitosis,and the first US Food and Drug Administration-approved indication of TTFields is recurrent glioblastoma.Nowadays,TTFields is also widely used in the treatment of other tumors.Herein the mechanism,characteristics and application of TTFields in the treatment of glioblastoma are summarized,and its advantages and disadvantages are analyzed.Finally,the application prospect of TTFields in the treatment of glioblastoma is discussed.

关 键 词：胶质母细胞瘤 肿瘤电场治疗 有丝分裂 综述 

分 类 号：R318[医药卫生—生物医学工程]