Carisolv化学机械法治疗乳牙龋病效果的Meta分析  

Effect of Carisolv chemomechanical method in treatment of deciduous tooth caries: A Meta-analysis

作　　者：赵媛[1] 刘大勇[2] 田咏 白大兵[1] ZHAO Yuan;LIU Dayong;TIAN Yong;BAI Dabing(Department of Stomatology,Tianjin Haihe Hospital,Tianjin 300350,China;Department of Endodontics,Stomatology Hospital,Tianjin Medical University,Tianjin 300070,China;Department of Rehabilitation,Tianjin Haihe Hospital,Tianjin 300350,China)

机构地区：[1]天津市海河医院口腔科,天津300350 [2]天津医科大学口腔医院牙体牙髓科,天津300070 [3]天津市海河医院康复科,天津300350

出　　处：《吉林大学学报（医学版）》2021年第3期694-700,共7页Journal of Jilin University：Medicine Edition

基　　金：国家自然科学基金项目(81670953);天津市科学技术委员会科学技术普及项目(20KPHDRC00060)。

摘　　要：目的:探讨Carisolv化学机械法用于儿童乳牙龋病治疗的效果,为该疗法广泛应用于临床提供循证医学依据。方法:计算机检索PubMed、中国知网(CNKI)、Medline、Wiley Online Library、万方和维普数据库,检索时限均为建库至2020年10月31日,筛选符合纳入标准的完全随机对照试验进行Meta分析。结果:最终纳入11个完全随机对照试验,共645例患者,1051颗患牙。采用Carisolv化学机械法患者的无痛率明显高于采用其他传统龋病治疗方法(OR=4.84,95%CI:3.44~6.81,Z=9.04,P<0.01),且治疗后并发症发生率较低(RR=0.37,95%CI:0.21~0.63,Z=3.60,P=0.0003)。儿童患者选择再次治疗的方法时更倾向于Carisolv化学机械法,但偏好性比较差异无统计学意义(OR=16.99,95%CI:1.50~192.31,Z=2.29,P=0.02)。结论:接受Carisolv化学机械法治疗的儿童患者疼痛和并发症均更少,该方法也更易被儿童接受,是一种非常适合用于儿童乳牙龋病治疗的技术。Objective:To explore the effect of Carisolv chemomechanical method in treatment of deciduous tooth caries in the children,and to provide the evidence-based medical basis for the extensive application of this method in the clinical practice.Methods:PubMed,CNKI,Medline,Wiley Online Library,Wanfang and Weipu databases were searched by computer from inception to October 31,2020.Meta-analysis was conducted on the complete randomized controlled trials that met the inclusion criteria.Results:A total of 11 completely randomized controlled trials involving 1051 teeth of 645 patients were included.The painless rate of Carisolv chemomechanical method was significantly higher than other traditional methods(OR=4.84,95%CI:3.44-6.81,Z=9.04,P<0.01),and the incidence of postoperative complications of the patients treated with Carisolv chemomechanical method were lower than those of other traditional methods(RR=0.37,95%CI:0.21-0.63,Z=3.60,P=0.0003).The pediatric patients were more inclined to Carisolv chemomechanical method when choosing the retreatment method,but the difference in preference was not statistically significant(OR=16.99,95%CI:1.50-192.31,Z=2.29,P=0.02).Conclusion:The pediatric patients treated with Carisolv chemomechanical method are less likely to suffer from pain and complications,and this method is more likely to be accepted by the children.Carisolv is a suitable technique for the caries of children’s deciduous teeth.

关 键 词：CARISOLV 化学机械法 乳牙 龋病 META分析 

分 类 号：R781.1[医药卫生—口腔医学]