牛黄类药材及牛胆的红外光谱特征性分析与研究  

Analysis and research of succession medicinal substances of cow-bezoar and cattle bile with infrared spectroscopy

作　　者：熊婧[1] 何兰[1] 魏锋[1] 马双成[1] 石岩[1] XIONG Jing;HE Lan;WEI Feng;MA Shuang-cheng;SHI Yan(National Institutes for Food and Drug Control,Beijing 102629,China)

机构地区：[1]中国食品药品检定研究院,北京102629

出　　处：《药物分析杂志》2021年第4期735-740,共6页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:对牛黄类药材及牛胆的红外光谱进行特征性分析和研究。方法:使用溴化钾压片法对样品进行红外光谱测定,以溴化钾作空白,每批样品扫描32次,分辨率设为4 cm^(-1),扫描范围为4000~400 cm^(-1)。结果:牛黄类药材及牛胆粉在3400、1725、1650、1555、1450、1250、1218、1046和1000~900 cm^(-1)的波数范围具有一定的特征性。结论:红外光谱可快速表征牛黄类药材的特征,在牛黄类药材的特征性研究中具有较好的应用。Objective:To study and analyze succession medicinal substances of cow-bezoar and cattle bile with infrared spectroscopy.Methods:The infrared spectrum determination was performed by potassium bromide pellet technique with potassium bromide used as blank and 4 cm^(-1) set as resolution,in the wave-number range of 4000-400 cm^(-1).Results:The peaks at 3400 cm^(-1),1725 cm^(-1),1650 cm^(-1),1555 cm^(-1),1450 cm^(-1),1250 cm^(-1),1218 cm^(-1),1046 cm^(-1) and 1000-900 cm^(-1) indicated differences among these succession medicinal substances of cow-bezoar and cattle bile.Conclusion:Infrared spectrum can quickly characterize the characteristics of succession medicinal substances of cow-bezoar,and can be applyed in the characteristics study of these medicines.

关 键 词：牛黄 体外培育牛黄 人工牛黄 牛胆 动物胆汁 特征识别 红外光谱 

分 类 号：R917[医药卫生—药物分析学]