Lynch综合征自我概念量表的汉化及信效度检验  

Chinese version of Lynch Syndrome Self-Concept Scale and its reliability and validity test

作　　者：贾书敏 吴晓丹[2] 张一恒 龚霓[3] 张美芬[3] Jia Shumin;Wu Xiaodan;Zhang Yiheng;Gong Ni;Zhang Meifen(First Ward of Department of Gastroenterology,Shandong Tumor Combat Research Institute(Shandong Cancer Hospital),Shandong First Medical University(Shandong Academy of Medical Sciences),Jinan 250117,China;Colorectal Department,Sun Yat-sen University Cancer Center,State Key Laboratory of Oncology in South China,Oncology Medicine Collaborative Innovation Center,Guangzhou 510060,China;School of Nursing,Sun Yat-sen University,Guangzhou 510080,China)

机构地区：[1]山东省肿瘤防治研究院(山东省肿瘤医院),山东第一医科大学(山东省医学科学院)消化内科一病区,济南250117 [2]中山大学肿瘤防治中心,华南肿瘤学国家重点实验室,肿瘤医学协同创新中心结直肠科,广州510060 [3]中山大学护理学院,广州510080

出　　处：《中华现代护理杂志》2021年第13期1689-1694,共6页Chinese Journal of Modern Nursing

摘　　要：目的:对Lynch综合征自我概念量表进行汉化并检验其信效度。方法:经过翻译、回译及文化调试,形成中文版Lynch综合征自我概念量表。于2018年11月—2019年2月,采用便利抽样法,选取广州市某三级甲等肿瘤专科医院119例Lynch综合征患者进行调查,计算中文版量表的信效度。量表的信度采用Cronbach'sα系数和折半信度表示;量表的内容效度采用内容效度指数(CVI)表示;采用探索性因子分析量表的结构效度。结果:中文版Lynch综合征自我概念量表内部一致性Cronbach'sα系数为0.944,折半信度为0.922,内容效度中量表水平的内容效度指数(S-CVI)为0.980,结构效度中通过探索性因子分析提取到3个公因子,分别代表了污名脆弱性维度、胃肠道焦虑维度以及污名脆弱性维度中2个正向问题,分别解释了总变异的49.392%、9.875%及8.007%,累计解释总变异的67.274%。结论:中文版Lynch综合征自我概念量表具有良好的信效度,适于在我国Lynch综合征患者中开展调查,用于测定患者遗传咨询和基因检测后对相关自我认知的影响,同时对于发展测量中国人群遗传性肿瘤综合征基因及遗传对患者的影响的工具具有借鉴意义。Objective To translate Lnych Syndrome Self-Concept Scale into Chinese and test its reliability and validity.Methods After translation,back translation and cultural adjustment,the Chinese version of Lynch Syndrome Self-Concept Scale was formed.From November 2018 to February 2019,the convenient sampling method was adopted to select 119 patients with Lynch syndrome in a ClassⅢGrade A tumor specialist hospital in Guangzhou for investigation,and the reliability and validity of the Chinese version of the scale were calculated.The reliability of the scale was expressed by Cronbach'sαcoefficient and split-half reliability;the content validity of the scale was expressed by content validity index(CVI);the construct validity of the scale was analyzed by exploratory factor analysis.Results Cronbach'sαcoefficient of internal consistency of the Chinese version of Lynch Syndrome Self-Concept Scale was 0.944,the split-half reliability was 0.922,and the scale-level content validity index(S-CVI)in the content validity was 0.980.In construct validity,three common factors were extracted by exploratory factor analysis,which represented stigma vulnerability dimension,gastrointestinal anxiety dimension and two positive problems of inxstigma vulnerability dimension,which explained respectively 49.392%,9.875%and 8.007%of the total variation and cumulatively explained 67.274%of the total variation.Conclusions Chinese version of Lynch Syndrome Self-Concept Scale has good reliability and validity.It is suitable for conducting surveys among Chinese patients with Lynch syndrome and it is used to determine the effects of genetic counseling and genetic testing on related self-cognition.At the same time,it is of reference significance for development of tools to measure the genes of hereditary tumor syndromes in Chinese population and the genetic influence on patients.

关 键 词：结直肠肿瘤 遗传性非息肉性 自我概念 量表 信度 效度 

分 类 号：R473[医药卫生—护理学]