Study on quality standard of Danmu exract syrup  

作　　者：Xiang-Yi Li Ming-Yan Zhou Zhen-Rui Xie Li Li Ai-Xia Liu Yu-Xin Zhang Wei-Yong Lai Jun-Qing Zhang Wei-Wei Guan 

机构地区：[1]Hainan Provincial Key Laboratory of R&D on Tropical Herbs,Haikou 571199 [2]School of Pharmaceutical Sciences Hainan Medicine University,Haikou 571199,China

出　　处：《Journal of Hainan Medical University》2021年第9期10-15,共6页海南医学院学报（英文版）

基　　金：Key science and technology project of Hainan province(No.ZDKJ201805)。

摘　　要：Objective:To establish the quality standard of Danmu exract syrup.Methods:TLC method was used to qualitatively identify Nauclea officinalis in Danmu exract syrup.The content of strictosamide and chlorogenic acid in Danmu exract syrup was determined by high efficiency axillary chromatography.Results:The spots were clear and there was no negative interference.The linear relationship of strictosamide was good in the range of 100~300ug/ml(R^(2)=0.9997).The average recovery was 99.1%and RSD was 1.16%(n=9).Chlorogenic acid had a good linear relationship in the range of 6.7~20.2ug/ml(R^(2)=0.9991).The average recovery was 99.9%and RSD was 1.10%(n=9).Conclusion:The standard is safe and reasonable,the method is simple,accurate and reproducible,and it can be used for the quality control of Danmu exract syrup.

关 键 词：Danmu exract syrup Quality standards STRICTOSAMIDE Chlorogenic acid High performance liquid CHROMATOGRAPHY Thin layer chromatography 

分 类 号：R28[医药卫生—中药学]