西安市体检人群甲状腺结节患病情况与血脂水平相关性分析  

Correlation analysis of the prevalence of thyroid nodules and blood lipid levels in physical examination population in Xi'an

作　　者：袁炜[1] 邢娟丽[2] 刘盈盈[1] 寇博[2] YUAN Wei;XING Juanli;LIU Yingying;KOU Bo(Department of Cardiovascular Medicine,the First Affiliated Hospital of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China;Department of Otolaryngology,the First Affiliated Hospital of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China)

机构地区：[1]西安交通大学第一附属医院心血管内科,陕西西安710061 [2]西安交通大学第一附属医院耳鼻喉科,陕西西安710061

出　　处：《现代肿瘤医学》2021年第11期1871-1874,共4页Journal of Modern Oncology

基　　金：陕西省自然科学基础研究计划(编号:2012JM4045,2019JM-575);西安交通大学第一附属医院科研发展基金(编号:2018MS-24)。

摘　　要：目的:了解普通体检人群甲状腺结节患病情况及与血脂水平的相关性,为甲状腺结节的防治提供依据。方法:收集2017年01月至2017年12月西安交通大学第一附属医院体检中心31796例普通体检者的检查结果,分析甲状腺结节检出率及与相关血脂指标(总胆固醇、低密度脂蛋白、高密度脂蛋白和甘油三酯)的关系,通过回归分析研究影响甲状腺结节患病的危险因素。结果:普通体检人群中甲状腺结节的患病率为25.02%,女性检出率高于男性(28.66%和22.43%,P<0.01),患病率随着年龄的增加而增大。多因素分析结果显示,年龄(OR:1.034)、女性(OR:0.533)、总胆固醇(OR:1.161)和低密度脂蛋白(OR:0.915)是甲状腺结节患病的危险因素(P均<0.05)。中老年(40~65岁)患者较中青年患者(40岁以下)更易出现低密度脂蛋白升高(P<0.01)。结论:甲状腺结节的发病有地域趋势,西安市普通体检人群甲状腺结节的患病主要与年龄(40~65岁)、性别(女性)、总胆固醇升高和低密度脂蛋白升高相关。Objective:To understand the prevalence of thyroid nodules and the relationship with blood lipid levels in the general physical examination population,and to provide evidence for the prevention and treatment of thyroid nodules.Methods:A total of 31796 subjects taken physical examin in the First Affiliated Hospital of Xi'an Jiaotong University from January 2017 to December 2017 were collected.Basic body indictors(age,weight,blood pressure)and related blood lipid indexes(total cholesterol,low-density lipoprotein,high-density lipoprotein and triglyceride)were performed.To investigated the risk factors for thyroid nodules through regression analysis.Results:The overall prevalence of thyroid nodules in the general physical examination population was 25.02%(7954/31796),and the prevalence of female was higher than that of male(28.66%vs 22.43%,P<0.01),and the prevalence increased with age.Multivariate analysis showed that age(OR:1.034),female(OR:0.533),total cholesterol(OR:1.161),and low-density lipoprotein(OR:0.915)were risk factors for thyroid nodules(all P<0.05).Middle-aged and elderly patients(40~65 years old)were more likely to have elevated LDL than middle-aged and young patients(under 40 years old)(P<0.01).Conclusion:The incidence of thyroid nodules has a regional difference.The prevalence of thyroid nodules in the general physical examination population in Xi'an was mainly related to age(40~65 years old),gender(female),elevated total cholesterol and elevated low-density lipoprotein.

关 键 词：甲状腺结节 血脂 检出率 相关性 

分 类 号：R730.231[医药卫生—肿瘤]