广西地区HIV并腹泻患者结肠镜检查价值的研究  

The value of colonoscopy in HIV patients with diarrhea in Guangxi

作　　者：谢志满 董文逸[2] 彭认平[2] 阮光靖[2] 牟敏红[2] XIE Zhi-man;DONG Wen-yi;PENG Ren-ping;RUAN Guang-jing;MOU Min-hong(Guangxi AIDS Clinical Treatment Center,Nanning530023,China;不详)

机构地区：[1]广西艾滋病临床治疗中心,南宁530023 [2]南宁市第四人民医院

出　　处：《医学动物防制》2021年第4期339-341,共3页Journal of Medical Pest Control

基　　金：南宁市科学研究与技术开发项目(20173157-3);广西艾滋病防治研究重点实验室(gklapt201703)。

摘　　要：目的了解广西地区HIV并腹泻患者行结肠镜检查的价值,为临床诊断、治疗提供帮助。方法对2017年1月至2019年12月间在广西艾滋病临床治疗中心(南宁)住院诊断为HIV并腹泻、非HIV并腹泻的患者行结肠镜检查,发现病变组织行病理检查,所有患者常规行大便病原学检查,结合临床做出诊断。结果86例HIV并腹泻患者中大便培养出病原菌9例,结合临床诊断感染性肠炎9例(10.5%),行结肠镜检查后结合病理、临床诊断肠道病变62例(72.1%),两者检出率差异有统计学意义(χ^(2)=73.52,P<0.05),HIV并腹泻患者感染性肠炎患病率37.2%,非HIV患病率11.8%,两者差异有统计学意义(χ^(2)=12.88,P<0.05)。结论HIV并腹泻患者大便病原学检查阳性率低,感染性肠炎患病率更高,临床诊断困难,建议尽快行肠镜检查,明确病因为患者治疗提供帮助。Objective To understand the value of colonoscopy for HIV patients with diarrhea in Guangxi,and provide help for clinical diagnosis and treatment.Methods Colonoscopy was performed on hospitalized patients diagnosed as HIV with diarrhea and non-HIV with diarrhea in Guangxi clinical treatment center(Nanning)from January 2017 to December 2019.The pathological examination was carried out with the positive pathological tissues.All patients were routinely examined for fecal etiology,and clinical diagnosis was made.Results Among the 86 HIV patients with diarrhea,9 cases of pathogenic bacteria were cultured in feces.The 9 cases(10.5%)were diagnosed with infectious enteritis in combination with clinical diagnosis,while 62 cases(72.1%)were diagnosed with intestinal lesions in combination with pathology and clinical diagnosis after colonoscopy.The difference in detection rate between the two was statistically significant(χ^(2)=73.52,P<0.05).The rate of HIV with diarrhea and non-HIV with diarrhea were 37.2%and 11.8%respectively,whose difference was statistically significant.(χ^(2)=12.88,P<0.05).Conclusion The positive rate of fecal pathogen examination is low in HIV patients with diarrhea.Infectious enteritis is more common,and the clinical diagnosis is difficult.Therefore,it is recommended to perform colonoscopy as soon as possible,to make clear the disease and provide help for the patient’s treatment.

关 键 词：艾滋病 HIV感染者 腹泻 结肠镜 感染 

分 类 号：R574[医药卫生—消化系统]