羊膜匀浆液生物学特性研究进展  

Advances in biological characteristics of amniotic membrane extraction

作　　者：胡淑娴 张文佳 胡竹林 Hu Shuxian;Zhang Wenjia;Hu Zhulin(Kunming Medical University,650504;Yunnan Eye Institute,Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology,Yunnan Provincial Second People's Hospital,Affiliated Hospital of Yunnan University,Kunming 650021,China)

机构地区：[1]昆明医科大学,650504 [2]云南大学附属医院云南省第二人民医院云南省眼科研究所云南省眼科疾病预防防治重点实验室,昆明650021

出　　处：《国际眼科纵览》2021年第2期130-134,共5页International Review of Ophthalmology

基　　金：云南省科技厅昆明医科大学应用基础研究联合专项(202001AY070001-255);2018年云南省卫生科技计划项目(2018NS0012)。

摘　　要：羊膜作为生物膜其保存成本较高,无法持续地对创面输送细胞因子等。羊膜相关制品保留羊膜的一定特性,弥补其不足,为羊膜制品在临床上的应用拓宽了道路。羊膜相关制品的基础为羊膜匀浆。本文将羊膜匀浆液生物学特性(低免疫原性、抗免疫反应、促进伤口愈合、抗眼部新生血管形成、抑制瘢痕形成、抗菌和抑制癌细胞生长等)的研究进展做一综述。As a biofilm,amniotic membrane has been used in the medical field for a long time.However,it has disadvantages such as high preservation cost and inability to continuously deliver cytokines to the wound surface.With the research on the active components of amnion,amnion-related products have come out,which retain certain characteristics of amnion,make up for the deficiency of amnion,and broaden the way for the clinical application of amnion products.The basis of amniotic membrane related products is amniotic membrane homogenate.Serum biological characteristics(low immunogenicity and immune response,promote wound healing,anti angiogenesis formation,inhibit scar formation,antibacterial and antimicrobial cancer cell growth,etc.)of amniotic membrane homogenate were reviewed in this paper.

关 键 词：羊膜 羊膜匀浆液 生物特性 

分 类 号：R77[医药卫生—眼科]