基于TiO_(2)-ZnPc(NH_(2))_(4)复合材料的光电化学传感器检测抗坏血酸  

A photoelectrochemical sensor based on Ti_(O)-ZnPc(NH_(2))_(4) composite material for the detection of ascorbic acid

作　　者：黎雪英 李晓坤[1] 冯素香[1] 农翠洁 LI Xueying;LI Xiaokun;FENG Suxiang;NONG Cuijie(College of Pharmacy,Henan University of Traditional Chinese Medicine,Zhengzhou 450046)

机构地区：[1]河南中医药大学药学院,郑州450046

出　　处：《分析试验室》2021年第5期598-604,共7页Chinese Journal of Analysis Laboratory

摘　　要：建立一种快速检测抗坏血酸的光电化学方法。运用固相法合成四氨基锌酞菁(ZnPc(NH_(2))_(4)),并与纳米TiO_(2)掺杂后修饰ITO电极,制备TiO_(2)-ZnPc(NH_(2))_(4)/ITO工作电极。通过扫描电子显微镜(SEM)、傅里叶变换红外光谱仪(FTIR)、紫外可见光分光光度计(UV-vis)对材料进行表征,通过交流阻抗技术(EIS)、电流时间曲线法(i-t)研究光电化学(PEC)传感器的性能。结果表明,光电流响应强度与抗坏血酸(AA)的浓度成正比,在0.25~670μmol/L范围内呈良好的线性关系,检出限为0.0642μmol/L。本方法应用于维C银翘颗粒、维生素C片以及尿样中AA含量的检测,其回收率分别为103.6%,101.9%,102.4%,相对标准偏差(RSDs)均小于5.0%,方法可用于实际样品的检测。In this work,a rapid photoelectrochemical( PEC) method for the detection of ascorbic acid was established. The tetraaminozinc phthalocyanine( ZnPc(NH2)4) was synthesized successfully by solid phase method. Then,the ITO electrode was modified by the composite of ZnPc(NH2)4 doped titanium dioxide(TiO2)nanoparticles,named as TiO2-ZnPc( NH2)4/ITO working electrode. The composite materials were characterized by scanning electron microscopy( SEM),fourier transform infrared spectrometer( FTIR),and ultraviolet-visible spectrophotometer( UV-vis). Further more,the impedance spectroscopy( EIS) and chronoamperometry( i-t)technologies were used to study the PEC performance of the sensor. The results showed that the photocurrent response intensity was directly proportional to the concentration of ascorbic acid( AA),showing a good linear relationship in the range of 0. 25-670 μmol/L,with detection limit of 0. 0642 μmol/L. The concentrations of AA in vitamin C Yin Qiao tablets,vitamin C tablets,and urine samples were measured. The recoveries were103. 6%,101. 9% and 102. 4%,respectively,with the relative standard deviations( RSDs) below 5. 0%. The method could be used for the detection of actual samples.

关 键 词：光电化学 纳米二氧化钛 四氨基锌酞菁 抗坏血酸 

分 类 号：O657.1[理学—分析化学]