肝原发性神经内分泌肿瘤MRI分析  

MRI analysis of primary hepatic neruoencomrine tumors

作　　者：何莎莎[1] 王青乐 周旭峰[1] HE Shasha;WANG Qingle;ZHOU Xufeng(Department of Imaging, Luoyang Central Hospital Henan Province, Luoyang 471000, P.R.China;Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R.China)

机构地区：[1]河南省洛阳市中心医院医学影像科,河南洛阳471000 [2]复旦大学附属中山医院放射科,上海200032

出　　处：《医学影像学杂志》2021年第5期818-821,共4页Journal of Medical Imaging

摘　　要：目的探讨肝脏原发性神经内分泌肿瘤(hepatic neuroendocrine tumor,HENT)MRI特征性表现。方法回顾性分析经手术病理证实为肝脏原发性神经内分泌肿瘤的9例患者MRI平扫及增强影像资料,总结特征表现。结果9例患者中男性4例,女性5例,平均年龄60岁;病灶直径平均为7.8 cm。8例表现为单发或多发实性肿块,内见囊变坏死;2例病灶内见出血,边界清楚,周围肝血管受压;增强扫描病灶8例动脉期呈不均匀明显强化,门静脉期、平衡期呈持续性强化,1例轻度强化;6例可见环形强化的包膜。各期强化程度与肝组织对照,P=0.028、0.005、0.001,差异有统计学意义;ADC值与肝组织对照,P=0.071差异无统计学意义。G1级1例,G2级6例,G3级2例。结论肝原发性神经内分泌肿瘤有特征性MRI表现,实性肿块、内见囊变坏死、边界清、有包膜、动脉期明显强化,延迟期持续性强化均是其重要征象。Objective To explore the MRI characteristics of primary neuroendocrine tumor of liver.Methods Plain scan and enhanced imaging data of 9 patients with primary neuroendocrine tumor of the liver confirmed by operation and pathology were analyzed retrospectively,and the characteristics were summarized.Results Five women and four men,with an average age of 60±8.7 years,had lesions with a diameter of(7.8±3.1)cm;8 cases presented as single or multiple solid masses,with cystic necrosis and hemorrhage in 2 cases;There were hemorrhage in 2 cases,with clear boundary and compression of the peripheral hepatic vessels;8 cases of the lesions showed uneven and obvious enhancement in the arterial phase,persistent enhancement in the portal vein phase and the balance phase,and slight enhancement was found in 1 case;6 cases showed ring enhanced capsule.Compared with liver tissue,the degree of enhancement in each phase was statistically significant(P=0.028,0.005,0.001);There was no significant difference between ADC and liver tissue(P=0.071)(P<0.05).According to the classification of mitosis and Ki-67 index,1 case was grade G1,6 cases were grade G2 and 2 cases were grade G3.Conclusion The primary neuroendocrine tumor of the liver has characteristic MRI features,including solid mass,cystic necrosis,clear boundary,capsule,obvious enhancement in arterial phase and continuous enhancement in delayed phase.

关 键 词：肝脏 原发性 神经内分泌肿瘤 磁共振成像 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]