胃肠道间质瘤的多排螺旋CT表现与病理及危险度分级的相关性分析  

Correlation analysis between multidetector CT findings and pathology and risk classification in gastrointestinal stromal tumor

作　　者：李志坚[1] 王淑宝 徐骥 方威[2] LI Zhijian;WANG Shubao;XU Ji;FANG Wei(CT/MRI Room,the People's Hospital of Huangshan,Huangshan,Anhui Province 245000,China;Department of Pathology,the People's Hospital of Huangshan,Huangshan,Anhui Province 245000,China)

机构地区：[1]黄山市人民医院CT/MRI室,安徽黄山245000 [2]黄山市人民医院病理科,安徽黄山245000

出　　处：《实用放射学杂志》2021年第5期794-798,共5页Journal of Practical Radiology

摘　　要：目的探讨多排螺旋CT(MDCT)在不同风险的胃肠道间质瘤(GIST)中的预测价值.方法回顾性分析47例经病理及免疫组化证实的49个原发性GIST病灶的患者术前CT图像,并通过分析GIST的CT表现与不同病理风险进行比较.统计学方法采用Fisher精确检验,以P<0.05为差异有统计学意义.结果本组GIST中19例为高度危险性病变,11例为中度危险,19例为低度危险.不同危险性的GIST在肿瘤生长部位、最大径、形状、平扫密度、强化模式及肿瘤坏死方面有统计学差异(P<0.05),而在肿瘤的生长方式、边界、强化程度、肿瘤血管、出血、钙化、溃疡及与胃肠道关系方面无统计学差异(P>0.05).结论GIST的部分CT征象对于肿瘤的危险度评估具有重要价值.形状不规则的较大肿块、CT平扫密度不均匀、异质强化模式及肿瘤坏死,提示GIST为高度危险性.Ohjective To explore the predictive value of multidetector CT(MDCT)in gastrointestinal stromal tumor(GIST)with different risks.MethodsThe preoperative CT images of 47 patients with 49 primary GIST confrmed by pathology and immunohistochemistry were analyzed retrospectively,and the CT findings of GIST were compared with different risks of pathologic findings.The Fisher's exact test was used,and the difference was considered statistically significant at P<0,05.Results In this group,19 cases of GIST were at high-rsk,ll at moderate-risk,and other 19 at low-risk.Statistical differences(P<0.05)in tumor growth site,maximum diameter,shape,plan CT density,enhancement pattern and tumor necrosis were found between different risk grades.However,there were no statistical differences in tumor growth pattern,boundary,degre of enhancement,vessels in or around the tumor,bleeding,calification,ulcer,and the relationship with the gastrointestinal tract among different risk grades(P>0.05).Conclusion Some CT features have significant value for risk assessment of CGIST.GIST with larger size irregular shape,uneven density on plan CT,heterogeneous enhancementpattern and tumor necrosis suggest high-risk.

关 键 词：胃肠道间质瘤 计算机体层成像 病理学 危险度分级 

分 类 号：R735.2[医药卫生—肿瘤] R814.42[医药卫生—临床医学]