佛山地区学龄期儿童Hp感染流行病学特征及与儿童生长发育关系的研究  

Epidemiological characteristics of Hp infection in school-age children in Foshan area and its relationship with children’s growth and development

作　　者：何昀 黄为民[2] 刘志刚[1] 罗威耀 林青梅 叶星光 廖旺 何小城 HE Yun;HUANG Weimin;LIU Zhigang;LUO Weiyao;LIN Qingmei;YE Xingguang;LIAO Wang;HE Xiaocheng(Department of Pediatrics,Foshan Maternal and Child Health Hospital,Southern Medical University,Foshan,528000,China;The First Clinical College of Southern Medical University)

机构地区：[1]南方医科大学附属佛山市妇幼保健院儿科,广东佛山528000 [2]南方医科大学第一临床医学院

出　　处：《中国中西医结合消化杂志》2021年第5期346-350,共5页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：目的:探究佛山地区学龄期儿童Hp感染流行病学特征及与儿童生长发育的关系。方法:通过三阶段抽样法选取2019年1月-2020年6月于佛山地区小学就读的一~六年级学龄期儿童共1200例,采用尿素13C呼气试验方法对研究对象进行Hp感染检测,并结合问卷调查结果及临床资料进行统计学分析。结果:1200名学龄儿童Hp总感染率为33.58%;男性Hp感染率(32.26%)与女性Hp感染率(34.86%)差异无统计学意义(P>0.05),农村儿童Hp感染率(40.44%)明显高于城镇儿童(26.82%),差异有统计学意义(P<0.05);6~8岁儿童Hp感染率(22.76%)明显低于8~10岁儿童(33.01%)和10~12岁儿童(44.84%),差异有统计学意义(P<0.05),8~10岁儿童Hp感染率明显低于10~12岁儿童,差异有统计学意义(P<0.05);Hp感染儿童父母身高、出生体重、足月率、母乳喂养率与Hp未感染儿童差异无统计学意义(P>0.05),Hp感染儿童WHZ<-1发生率、HAZ<-1发生率、WAZ<-1发生率均远高于未感染儿童(P<0.05)。结论:学龄期儿童Hp感染与其性别并无明显关系,农村儿童Hp感染率明显高于城镇儿童,学龄期儿童Hp感染率随着其年龄的增加而增加,且对于儿童的生长发育情况有明显影响。Objective: To explore the epidemiological characteristics of Helicobacter pylori infection in school-age children in Foshan and its relationship with growth and development. Methods: We used a three-stage sampling method to select a total of 1200 cases of school-age children in grades one to six who were studying in primary schools in Foshan from January 2019 to June 2020, and then used the 13C-UBT method to test the subjects for Hp infection, combined the results of the questionnaire survey and clinical data for statistical analysis. Results: The total Hp infection rate among 1200 school-age children was 33.58%.The total Hp infection rate of 1200 school-age children was 33.58%;the Hp infection rate of males(32.26%) was not significantly different from that of females(34.86%)(P>0.05), and the Hp infection rate of rural children(40.44%) was significantly higher than that Hp infection rate in urban children(26.82%)(P<0.05);Hp infection rate in children aged 6-8(22.76%) was significantly lower than that in children aged 8-10(33.01%) and Hp infection in children aged 10-12(44.84%)Hp infection rate of children aged 8-10 was significantly lower than that of children aged 10-12(P<0.05).There was no significant difference in the height, weight, full-term rate, breastfeeding rate, and Hp-uninfected children of children with Hp infection(P>0.05).The incidence of Hp-infected children with WHZ<-1,HAZ<-1 and WAZ<-1 was much higher than that of uninfected children(P<0.05). Conclusion: There is no obvious relationship between Hp infection in school-age children and their sex. The Hp infection rate in rural children is significantly higher than that in urban children. The Hp infection rate in school-age children increases with their age and has a significant impact on the growth and development of children.

关 键 词：幽门螺杆菌 儿童 流行病学 生长 发育 

分 类 号：R573[医药卫生—消化系统]