后交通动脉圆锥的形态学及血流动力学应力特点分析  

Morphological and hemodynamic stress characteristics of infundibular dilatation of the posterior communicating artery

作　　者：张坤[1] 夏金超 王子亮[1] 李天晓[1] 李钊硕 高不郎 高慧丽[1] 汪勇锋[1] Zhang Kun;Xia Jinchao;Wang Ziliang;Li Tianxiao;Li Zhaoshuo;Gao Bulang;Gao Huili;Wang Yongfeng(Cerebrovascular Department,Henan Provincial People's Hospital A ffiliated to Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学附属河南省人民医院脑血管科,郑州450000

出　　处：《中华神经医学杂志》2021年第5期507-510,共4页Chinese Journal of Neuromedicine

基　　金：河南省医学科技攻关计划省部共建项目(SBGJ202003006)。

摘　　要：目的探讨后交通动脉圆锥的形态学及血流动力学应力特点。方法对河南省人民医院脑血管科自2018年1月至2020年5月收治的因疑诊后交通动脉瘤行数字减影血管造影(DSA)检查而发现存在后交通动脉圆锥的30例患者(观察组),应用DSA技术测量并结合计算机模拟血流动力学采线方法定量分析后交通动脉与颈内动脉的弯曲角度后交通动脉圆锥处血流动力学应力参数如总压力.剪切力等,以同期收治的后交通动脉正常的30例非颅内动脉瘤患者为对照组。结果对照组的后交通动脉与领内动脉的弯曲角度为[(80.1±8.4)°],明显高于观察组[(73.2±5.8)°],差异有统计学意义(P<0.05);观察组后交通动脉圆锥处的血流剪切力、总压力分别为(8.32±0.70)Pa、(85.61±6.04)Pa,均明显高于对照组正常后交通动脉相同部位处[(3.95±0.28)Pa、(25.72±7.18)Pa],差异均有统计学意义(P<0.05)。结论后交通动脉圆锥处的局部血流应力与正常后交通动脉相同部位处存在显著性差异,其可能在后交通动脉瘤的形成中具有重要作用。Objective To investigate the morphological and hemodynamic stress characteristics of infundibular dilatation of the posterior communicating artery.Methods From January 2018 to May 2020.30 patients with infundibular dilatation of the posterior communicating artery(observation group)found by digital substruction angiography(DSA)for suspecting as having equivocal posterior communicating artery aneurysm in our hospital were selected.The angle between posterior communicating artery and internal carotid artery,and hemodynamics stress parameters at the infundibular dilatation of the posterior communicating artery(total pressure and shear force)were measured by DSA and quantitatively analyzed by computational fluid dynamics methods.Thirty patients without intracranial aneurysm and with normal posterior communicating arteries admitted to our hospital at the same period were used as control group.Results The mean value of the bending angle between the posterior communicating artery and internal carotid artery in the control group was([80.1±8.4)°),which was significantly higher than that in the observation group([73.2±5.8]°,P<0.05).The shear force and total pressure of infundibular dilatation of the posterior communicating artery of the observation group([8.32±0.70]Pa and[85.61±6.04]Pa),which w ere significantly higher than those of the control group at the same locations[(3.95±0.28)Pa and(25.72±7.18]Pa,P<0.05).Conclusion There are significant differences in hemodynamic stress between the normal posterior communicating artery and the infundibular dilatation of the posterior communicating artery,which might play an important role in triggering the formation of aneurysms.

关 键 词：后交通动脉 动脉圆锥 血流动力学应力 形态学 

分 类 号：R743.4[医药卫生—神经病学与精神病学]