加味左金丸联合铝碳酸镁治疗反流性食管炎临床研究  

Clinical Study on Modified Zuojin Bolus Combined with Aluminum Magnesium Carbonate for Reflux Esophagitis

作　　者：李佶 余红军 LI Ji;YU Hongjun

机构地区：[1]龙游县人民医院内科,浙江龙游324400 [2]杭州市中医院感染科,浙江杭州310009

出　　处：《新中医》2021年第9期10-13,共4页New Chinese Medicine

摘　　要：目的:观察加味左金丸联合铝碳酸镁治疗反流性食管炎的临床效果。方法:将80例反流性食管炎炎患者,按照不同治疗方法分为A组与B组,均为40例,A组给予铝碳酸镁治疗,B组给予加味左金丸联合铝碳酸镁治疗。对比2组患者的临床症状积分、临床症状改善效果、内镜疗效以及生活质量。结果:2组治疗前的临床症状积分对比,差异无统计学意义(P>0.05)。治疗后,2组积分较前改善,B组治疗后临床症状积分低于A组(P<0.05)。B组临床症状改善效果总有效率高于A组(P<0.05)。B组内镜疗效的总有效率高于A组(P<0.05)。2组治疗前健康状况调查简表(SF-36)评分比较,差异无统计学意义(P>0.05);治疗后,2组生活质量较前改善,B组治疗后的SF-36评分高于A组(P<0.05)。结论:加味左金丸联合铝碳酸镁治疗反流性食管炎的临床效果理想,可明显改善临床症状,且可提高患者的内镜疗效与生活质量。Objective:To observe the clinical effect of modified Zuojin bolus combined with aluminum magnesium carbonate for reflux esophagitis.Methods:A total of 80 cases of patients with reflux esophagitis were divided into Group A and Group B according to different treatment methods,40 cases in each group.Group A was treated with aluminum magnesium carbonate,and Group B was treated with modified Zuojin bolus combined with aluminum magnesium carbonate.The scores and improvement effect of clinical symptoms,the curative effect of endoscopy and the quality of life in the two groups were compared.Results:Before treatment,there was no significant difference being found in the comparison of clinical symptom scores between the two groups(P>0.05).After treatment,the clinical symptom scores in the two groups were improved when compared with those before treatment,and the score in Group B was lower than that in Group A(P<0.05).The total effective rate of clinical symptom improvement in Group B was higher than that in Group A(P<0.05).The total effective rate of the curative effect of endoscopy in Group B was higher than that in Group A(P<0.05).Before treatment,there was no significant difference being found in the comparison of the MOS item short from health survey(SF-36)scores between the two groups(P>0.05).After treatment,the quality of life in the two groups was improved when compared with that before treatment,and the SF-36 score in Group B was higher than that in Group A(P<0.05).Conclusion:The therapy of modified Zuojin bolus combined with aluminum magnesium carbonate has ideal clinical effect in treating reflux esophagitis,which can significantly improve the clinical symptoms,the curative effect of endoscopy and quality of life in patients.

关 键 词：反流性食管炎 加味左金丸 铝碳酸镁 内镜疗效 生活质量 

分 类 号：R571[医药卫生—消化系统]