Acute pancreatitis may be a pathogenic factor of fulminant type 1 diabetes mellitus  

作　　者：Ya-Ning Chen Ming-Wei Zhao Jia Cui He-Bin Yao 

机构地区：[1]Department of Endocrinology,the Sixth Medical Center of PLA General Hospital,Beijing 100048,China

出　　处：《Chinese Medical Journal》2021年第9期1127-1128,共2页中华医学杂志（英文版）

摘　　要：To the Editor:Fulminant type 1 diabetes mellitus(FT1DM)is characterized by a rapid loss ofβ-cell functions,negative antibody to islet cells,ketoacidosis,and elevated pancreatic enzymes.[1]In a nationwide survey in Japan,elevated pancreatic enzymes and abdominal pain were found in 98%and 70%of patients with ketoacidosisonset FT1DM,respectively.However,abdominal computed tomography(CT)showed no abnormalities.The increased pancreatic enzymes were related to diabetic ketoacidosis.Several Japanese scholars have reported that FT1DM appeared after acute pancreatitis(AP).So far,no such cases have been reported in China.Here,we report two cases of FT1DM following AP,review previous cases,and speculate the relationship between AP and FT1DM.Informed consents were obtained from both patients.

关 键 词：ELEVATED PANCREATITIS MELLITUS 

分 类 号：R576[医药卫生—消化系统] R587.2[医药卫生—内科学]