Sofia远端通路导管抽吸术治疗急性动脉闭塞的效果  

Effect of Sofia distal access catheter aspiration in the treatment of acute arterial occlusion

作　　者：江顺福 黄澄鹏 曹铭华 吴明超 邹永周 王璐 JIANG Shun-fu;HUANG Cheng-peng;CAO Ming-hua;WU Ming-chao;ZOU Yong-zhou;WANG Lu(Department of Neurology,Jingdezhen No.1 People′s Hospital,Jiangxi Province,Jingdezhen 333000,China)

机构地区：[1]江西省景德镇市第一人民医院神经内科,江西景德镇333000

出　　处：《中国当代医药》2021年第16期4-7,共4页China Modern Medicine

基　　金：江西省景德镇市医药卫生科技计划项目(20201SFZC002)。

摘　　要：目的探讨Sofia远端通路导管抽吸术治疗急性动脉闭塞的效果。方法选取2019年1月~2020年6月于江西省景德镇市第一人民医院接受取栓治疗的60例急性动脉闭塞患者作为研究对象,通过随机数字表法分为对照组与研究组,每组各30例,分别给予支架取栓治疗、Sofia远端通路导管抽吸术治疗。比较两组患者的手术治疗情况、并发症发生情况、美国国立卫生研究院卒中量表(NIHSS)评分、神经内科医师护士常用判断病情伤残表(MRS)评分。结果研究组患者穿刺到血管成功再通耗时短于对照组[(14.30±2.10 vs.29.55±4.56)min],差异有统计学意义(P<0.05)。研究组与对照组患者发病到血管成功再通耗时[(255.00±69.00 vs.260.00±79.00)min]、1次成功再通率(73.33%vs.63.33%)及DSA灌注评分(mTICI)2b/3级(66.67%vs.53.33%)、mTICI 3级(40.00%vs.33.33%)占比比较,差异无统计学意义(P>0.05)。研究组与对照组患者手术并发症总发生率(23.33%vs.26.67%)比较,差异无统计学意义(P>0.05)。研究组与对照组患者术前NIHSS评分[(11.26±3.90 vs.11.28±3.88)分]比较,差异无统计学意义(P>0.05);两组患者术后24、48 h的NIHSS评分均低于术前,差异有统计学意义(P<0.05);研究组与对照组患者术后24 h的NIHSS评分[(10.61±3.68 vs.10.59±3.70)分]、术后48 h的NIHSS评分[(9.85±3.44 vs.9.87±3.42)分]比较,差异无统计学意义(P>0.05)。术后90 d,研究组MRS评分<2分24例,≥2分6例,对照组MRS评分<2分25例,≥2分5例;两组MRS评分比较,差异无统计学意义(P>0.05)。结论Sofia远端通路导管抽吸术同支架取栓术比较,两种术式的安全性与疗效近似,均能有效改善患者神经功能缺损情况及预后质量,但是前者穿刺到血管成功再通耗时较短,操作更加简便,临床实际应用时,医护人员要根据患者实际情况做出合理选择。Objective To investigate the effect of Sofia distal access catheter aspiration in the treatment of acute arterial occlusion.Methods From January 2019 to June 2020,60 patients with acute arterial occlusion who received thrombectomy treatment in Jingdezhen No.1 People′s Hospital,Jiangxi Province were selected as the research objects.They were divided into the control group and the study group by the random number table method,with 30 cases in each group,and they were given stent thrombus removal treatment and Sofia distal access catheter aspiration treatment respectively.The surgical treatment,incidence of complications,the National Institutes of Health stroke scale(NIHSS)score,and the modified Rankin scale(MRS)score commonly used to judge the condition and disability by neurosurgeon and nurses were compared in the two groups.Results The time from puncture to successful recanalization in the study group was shorter than that in the control group([14.30±2.10 vs.29.55±4.56]min),the difference was statistically significant(P<0.05).There were on statistically significant differences in the time from onset to successful recanalization([255.00±69.00 vs.260.00±79.00]min),first-time success recanalization rate(73.33%vs.63.33%),and proportions of DSA perfusion score(mTICI)2b/3(66.67%vs.53.33%)and mTICI 3(40.00%vs.33.33%)between the study group and the control group(P>0.05).There was no significant difference in the total incidence of surgical complications between the study group and the control group(23.33%vs.26.67%)(P>0.05).There was no significant difference in the NIHSS score before operation between the study group and the control group([11.26±3.90 vs.11.28±3.88]points)(P>0.05).The NIHSS scores of the two groups at 24 and 48 h after surgery were lower than those before surgery,and the differences were statistically significant(P<0.05).There were no statistically significant differences in the NIHSS scores at 24 h after surgery([10.61±3.68 vs.10.59±3.70]points)and 48 h after surgery([9.85±3.44 vs.9.87±3.42]p

关 键 词：Sofia远端通路导管 急性 动脉闭塞 取栓治疗 

分 类 号：R743[医药卫生—神经病学与精神病学]