Cholesterol gallstones:Focusing on the role of interstitial Cajal-like cells  

作　　者：Bei-Bei Fu Jian-Nan Zhao Shuo-Dong Wu Ying Fan 

机构地区：[1]Department of Health Management,Shengjing Hospital of China Medical University,Shenyang 110004,Liaoning Province,China [2]Department of General Surgery,Shengjing Hospital of China Medical University,Shenyang 110004,Liaoning Province,China

出　　处：《World Journal of Clinical Cases》2021年第15期3498-3505,共8页世界临床病例杂志

基　　金：National Natural Science Foundation of China,No.81000183;and Natural Science Foundation of Liaoning Province,No.20180550125.

摘　　要：with a complex and multifactorial etiology.Declined gallbladder motility reportedly contributes to CG pathogenesis.Furthermore,interstitial Cajal-like cells(ICLCs)are reportedly present in human and guinea pig gallbladder tissue.ICLCs potentially contribute to the regulation of gallbladder motility,and aberrant conditions involving the loss of ICLCs and/or a reduction in its pacing potential and reactivity to cholecystokinin may promote CG pathogenesis.This review discusses the association between ICLCs and CG pathogenesis and provides a basis for further studies on the functions of ICLCs and the etiologies of CG.

关 键 词：Interstitial Cajal-like cells Cholesterol gallstones Gallbladder motility Biliary system disease GALLSTONES 

分 类 号：R575.62[医药卫生—消化系统]