Acute inferior myocardial infarction in a young man with testicular seminoma:A case report  

作　　者：Alexandru Scafa-Udriste Nicoleta-Monica Popa-Fotea Vlad Bataila Lucian Calmac Maria Dorobantu 

机构地区：[1]Department of Cardio-Thoracic,University of Medicine and Pharmacy,Bucharest 050474,Romania [2]Department of Cardiology,Emergency Clinical Hospital,Bucharest 014461,Romania

出　　处：《World Journal of Clinical Cases》2021年第16期4040-4045,共6页世界临床病例杂志

基　　金：Executive Agency for Higher Education,Research,Development and Innovation Funding,No.PN-III-P2-2.1-PED-2019-2434.

摘　　要：BACKGROUND Atherosclerosis represents the main cause of myocardial infarction(MI);other causes such as coronary embolism,vasospasm,coronary-dissection or drug use are much rarely encountered,but should be considered in less common clinical scenarios.In young individuals without cardiovascular risk factors,the identification of the cause of MI can sometimes be found in the medical history and previous treatments undertaken.CASE SUMMARY We present the case of a 34-year-old man presenting acute inferior ST-elevation MI without classic cardiac risk factors.Seven years ago,he suffered from orchidopexy for bilateral cryptorchidism,and was recently diagnosed with right testicular seminoma for which he had to undergo surgical resection and chemotherapy with bleomycin,etoposide and cisplatin.Shortly after the first chemotherapy treatment,namely on day five,he suffered an acute MI.Angiography revealed a mild stenotic lesion at the level of the right coronary artery with suprajacent thrombus and vasospasm,with no other significant lesions on the other coronary arteries.A conservative treatment was decided upon by the cardiac team,including dual antiplatelets therapy and anticoagulants with good further evolution.The patient continued the chemotherapy treatment according to the initial plan without other cardiovascular events.CONCLUSION In young individuals with no cardiovascular risk factors undergoing aggressive chemotherapy,an acute MI can be caused by vascular toxicity of several anticancer drugs.

关 键 词：Testicular seminoma Myocardial infarction Non-atherosclerotic causes of myocardial infarction CHEMOTHERAPY Case report 

分 类 号：R737.21[医药卫生—肿瘤] R542.22[医药卫生—临床医学]