Parotid mammary analogue secretory carcinoma:A case report and review of literature  

作　　者：Feng-He Min Jia Li Bo-Qiang Tao Hui-Min Liu Zhi-Jing Yang Lu Chang Yu-Yang Li Ying-Kun Liu Yi-Wen Qin Wei-Wei Liu 

机构地区：[1]Department of Oral and Maxillofacial Surgery,Hospital of Stomatology,Jilin University,Changchun 130021,Jilin Province,China [2]Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling,Changchun 130021,Jilin Province,China [3]Department of Oral Implant,Hospital of Stomatology,Jilin University,Changchun 130021,Jilin Province,China [4]Department of Stomatology,Chongqing Medical University,Chongqing 400016,China

出　　处：《World Journal of Clinical Cases》2021年第16期4052-4061,共10页世界临床病例杂志

基　　金：International Science and Technology Cooperation Project of Jilin Province Science and Technology Department,China,No.20200801077GH;Science and Technology Project of Jilin Provincial Department of Finance,China,No.JCSZ2019378-8;Jilin Provincial Development and Reform Commission Project,China,No.2019C051-5.

摘　　要：BACKGROUND Mammary analogue secretory carcinoma(MASC)is a rare low-grade malignant salivary gland tumor.The morphological and immunohistochemical features of MASC closely resemble those of breast secretory carcinoma.The key characteristics of the lesion are a lack of pain and slow growth.There is no obvious specificity in the clinical manifestations and imaging features.The diagnosis of the disease mainly depends on the detection of the MASC-specific ETV6-NTRK3 fusion gene.CASE SUMMARY This report describes a rare case of a 32-year-old male patient who presented with a gradually growing lesion that was initially diagnosed as breast-like secretory carcinoma of the right parotid gland.Imaging and histological investigations were used to overcome the diagnostic difficulties.The lesion was managed with right parotidectomy,facial nerve preservation,biological patch implantation to restore the resulting defect,and postoperative radiotherapy.On postoperative follow-up,the patient reported a mild facial deformity with no complications,signs of facial paralysis,or Frey’s syndrome.CONCLUSION The imaging and histological diagnostic challenges for MASC are discussed.

关 键 词：Mammary analogue secretory carcinoma Salivary gland IMMUNOHISTOCHEMISTRY Total lobectomy of right parotid gland Case report 

分 类 号：R737.9[医药卫生—肿瘤]