Thymosin as a possible therapeutic drug for COVID-19:A case report  

作　　者：Qiong Na Zheng Mei Yan Xu Fang Min Gan Sha Sha Ye Hui Zhao 

机构地区：[1]Department of Infectious Diseases,The Affiliated Yueqing Hospital,Wenzhou Medical University,Yueqing 325600,Zhejiang Province,China

出　　处：《World Journal of Clinical Cases》2021年第16期4090-4094,共5页世界临床病例杂志

基　　金：The Project for Science and Technology of Wenzhou,No.Y2020278.

摘　　要：BACKGROUND There are no effective antiviral therapies for coronavirus disease 2019(COVID-19)at present.Although most patients with COVID-19 have a mild or moderate course of disease,up to 5%-10%of patients may have a serious and potentially life-threatening condition,indicating an urgent need for effective therapeutic drugs.The therapeutic effect of thymosin on COVID-19 has not been previously studied.In this paper,for the first time we report a case of thymosin treatment of COVID-19.CASE SUMMARY A 51-year-old man with imported COVID-19 was admitted with definite symptoms of chest tightness,chest pain,and fatigue.The polymerase chain reaction results for severe acute respiratory syndrome coronavirus 2 were negative.The antibody test was positive,confirming the diagnosis of COVID-19.As many orally administered drugs were not well tolerated due to gastrointestinal symptoms,an emergency use of thymosin,a polypeptide consisting of 28 amino acids,was administered by injection.Finally,after the implementation of the treatment program,symptoms and lung imaging improved significantly.CONCLUSION In this case report,it is confirmed that thymosin may help alleviate the severity of COVID-19 symptoms.

关 键 词：COVID-19 THYMOSIN SARS-CoV-2 Treatment Therapeutic drug Case report 

分 类 号：R563.1[医药卫生—呼吸系统]