supported by grants from the Key Project of the Chinese Ministry of Science and Technology(2017ZX102022022);the National Natural Science Foundation of China(81970522);the Key Research and Development Project of Shandong Province(2019GSF108023).
Background:It has been demonstrated that thymosinβ4(Tβ4)could inflect the severity of acute-on-chronic hepatitis B liver failure(ACHBLF),but the relationship between its methylation status and the prognosis of liver...
1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(Nos.ZYGD18021 and ZYJC18009).
Background:There is limited information about thymosinα1(Tα1)as adjuvant immunomodulatory therapy,either used alone or combined with other treatments,in patients with non-small cell lung cancer(NSCLC).This study aim...
The Project for Science and Technology of Wenzhou,No.Y2020278.
BACKGROUND There are no effective antiviral therapies for coronavirus disease 2019(COVID-19)at present.Although most patients with COVID-19 have a mild or moderate course of disease,up to 5%-10%of patients may have a ...
COVID-19 is known for its magical infectivity,fast transmission and high death toll based on the large number of infected people.From the perspective of the clinical manifestation,autopsy examination and pathophysiolo...
supported by the Foundation for Distinguished Young Talents in Higher Education of Guangdong Province, China (2016KQNCX019 and 2016KQNCX027);the National Natural Science Foundation of China (31571041);the Guangdong Provincial Department of Education Innovating Strong National Engineering Major Project (2014GKXM031);Guangdong Provincial Universities and Colleges Pearl River Scholar Funded Scheme (2016)
Activation of inflammatory responses regulates the transmission of pain pathways through an integrated network in the peripheral and central nervous systems.The immunopotentiator thymosin alpha-1(Tal)has recently been...
Objective: To investigate the effect of ulinastatin + thymosin adjuvant therapy on inflammatory and stress response in patients with severe pneumonia. Methods: A total of 66 patients with severe pneumonia who were dia...
As a result of increased prevalence of obesity worldwide, non-alcoholic fatty liver disease (NAFLD) has become one of the most common causes of chronic liver disease. Although most NAFLD cases remain benign, some prog...
Supported by National Foundation of Natural Sciences,China,No.81300293
AIMTo investigate the protective effect of a recombinant adeno-associated virus carrying thymosin β4 (AAV-Tβ4) on murine colitis via intracolonic administration.METHODSAAV-T...