The severe COVID-19: A sepsis induced by viral infection? And its immunomodulatory therapy  

作　　者：Hong-Yuan Lin 

机构地区：[1]Forth Medical Center,General Hospital of PLA,Beijing,China

出　　处：《Chinese Journal of Traumatology》2020年第4期190-195,共6页中华创伤杂志（英文版）

摘　　要：COVID-19 is known for its magical infectivity,fast transmission and high death toll based on the large number of infected people.From the perspective of the clinical manifestation,autopsy examination and pathophysiology,the essence of COVID-19 should be viewed as a sepsis induced by viral infection,and has the essential characteristics as sepsis induced by other pathogens.Therefore,in addition to etiological and supportive treatment,immunomodulatory therapy is also appropriate to severe COVID-19.Although there is still a lack of consensus on immunotherapy for sepsis so far,relatively rich experiences have been accumulated in the past decades,which will help us in the treatment of severe COVID-19.This article will elaborate immunotherapy of sepsis,though it may not be consistent.

关 键 词：COVID-19 SEPSIS Immunomodulatory therapy IMMUNOTHERAPY ULINASTATIN Thymosin a1 

分 类 号：R563.1[医药卫生—呼吸系统]