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SEVERE: 作品数：1284被引量：3513H指数：22; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：吴蔚杨康何萍夏梅杨孜更多>>; 相关机构：中山大学附属第一医院中南大学复旦大学第三军医大学西南医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家科技支撑计划更多>>

Genetic disorders leading to severe hyperlipidemia in children:A case report: 《World Journal of Clinical Cases》2025年第16期60-66,共7页Chun-Xin Jiang Yu-Lin Meng Dong Chen Lian-Ping Shi Guang Yang Yang Guo Bo Zhang Zi-Chen Zhai Zhi-Jian Wu Tie-Nan Liu Zhi-Jun Wang Xiao Tian Peng-Yu Su; Natural Science Foundation of Hebei Province,China,No.H2020209160;Scientific Research Projects in Chinese Medicine of Hebei Province,China,No.2019168.; BACKGROUND Alagille syndrome is a rare autosomal dominant genetic disorder involving multiple organ systems.Its most common manifestations are chronic cholestasis caused by intrahepatic bile duct deficiency and severe...; 关键词：HYPERLIPIDEMIA Alagille syndrome Genetic mutation JAG1 CHOLESTASIS Low density lipoprotein cholesterol Traditional Chinese medicine Case report

Diagnosis and surgical challenges of extremely severe head and lumbar disc herniation in young patients:A case report: 《World Journal of Clinical Cases》2025年第16期67-75,共9页Jun-Ge Zhou; BACKGROUND Lumbar disc extrusion,a common spinal disorder,is particularly uncommon in its severely displaced form,especially in young patients.This condition can pose diagnostic challenges due to its nonspecific prese...; 关键词：Lumbar disc extrusion Cephalad Open surgery Clinical implications Diagnostic assessment Case report

Nomogram for prediction of severe postoperative complications in elective hepato-pancreato-biliary surgery after COVID-19 breakthrough infection:A large multicenter study: 《Hepatobiliary & Pancreatic Diseases International》2025年第2期147-156,共10页Yun Yang Zheng Dang Liang Tang Peng Lu Shang Ma Jin Hou Ze-Ya Pan Wan Yee Lau Wei-Ping Zhou; supported by grants from the Science Fund for Creative Research Groups of the National Natural Science Founda-tion of China(81521091 and 82073031);the National Natural Sci-ence Foundation of China(92269204);Clinical Research Plan of SHDC(SHDC2020CR5007 and SHDC22020213)。; Background:Currently,there is a deficiency in a strong risk prediction framework for precisely evaluating the likelihood of severe postoperative complications in patients undergoing elective hepato-pancreatobiliary su...; 关键词：NOMOGRAM Severe postoperative complications Hepato-pancreato-biliary surgery COVID-19 Breakthrough infection

Multimodal diagnostic and surgical approach to spontaneous esophageal rupture induced by severe coughing: A case report: 《World Journal of Gastrointestinal Surgery》2025年第4期389-398,共10页Shu-Yun Xiong Chang-Jiang Liu Yong-Feng Li Han-Liang Zhang Xiao-Wei Chen Hai-Man Wang Ji-Cai Chen; Supported by Guangzhou Municipal Science and Technology Bureau,No.SL2024AD3JD0112.; BACKGROUND Boerhaave syndrome,or spontaneous esophageal rupture,is a rare and lifethreatening emergency,typically caused by a sudden increase in esophageal pressure due to violent coughing or vomiting.Early diagnosis ...; 关键词：Esophageal rupture SPONTANEOUS Boerhaave syndrome COUGH SEVERE Surgical treatment Diagnosis Differential Case report

Enhancing outcomes in severe lymphedema through combined treatment strategies: 《World Journal of Clinical Cases》2025年第12期70-73,共4页Aidan Shulkin Johnny I Efanov; Lymphedema,particularly in its advanced stages,presents significant challenges in treatment,often necessitating a combination of therapies to manage symptoms effectively and improve patient outcomes.This article revie...; 关键词：LYMPHEDEMA LYMPHANGITIS Lymphovenous anastomosis Complex decongestive therapy Quality of life Mobility

Identification of a pathogenic NHLRC1 variant in a consanguineous Pakistani family affected with severe and rapidly progressive Lafora disease: 《Acta Epileptologica》2025年第1期124-130,共7页Zain Aslam Bibi Zubaida Ranjha Khan Mazhar Badshah Muhammad Naeem; Zain Aslam(112-36551-2BM1-037);Bibi Zubaida(212-52789-2BM2-080);supported by the Higher Education Commission of Pakistan under Indigenous Ph.D.Fellowships Program.; Background Autosomal recessively inherited progressive myoclonic epilepsy of Lafora,which is also known as Lafora disease,is a fatal neurodegenerative disorder.It affects individuals in late childhood or early adolesc...; 关键词：Progressive myoclonic epilepsy Lafora bodies Laforin DNA sequencing Mutation

Clinical manifestation and management of severe blepharokeratoconjunctivitis combined with corneal perforation: 《International Journal of Ophthalmology(English edition)》2025年第2期229-236,共8页Xu Li Ping Hou Xiao-Lin Qi Su-Xia Li Wei-Yun Shi Hua Gao Ting Zhang; Supported by Key Technology Research and Development Program of Shandong Province(No.2022CXGC010505);Natural Science Foundation of Shandong Province(No.ZR2019BH065);Taishan Scholars Program(No.20221110);the Innovation Project of Shandong Academy of Medical Sciences.; AIM:To investigate the clinical signs of blepharokeratoconjunctivitis(BKC)and evaluate the efficacy of penetrating keratoplasty(PKP)for the disease.METHODS:Sixteen patients(16 eyes)with BKC complicated by corneal perf...; 关键词：blepharokeratoconjunctivitis corneal perforation penetrating keratoplasty

TavWA1 is critical for wheat growth by modulating cell morphology and arrangement: 《Journal of Integrative Plant Biology》2025年第1期71-86,共16页Guowei Chang Yue Li Lei Peng Chuncai Shen Yipeng Lu Wan Teng Yangyang Liu Yingchun Wang Weiqi Zhu Cuimin Liu Xue He Yiping Tong Xueqiang Zhao; financially supported by the Biological Breeding-National Science and Technology Major Project(2023ZD0406802);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA24010202)。; Plant growth is determined by the production of cells and initiation of new organs.Exploring genes that control cell number and cell size is of great significance for understanding plant growth regulation.In this stud...; 关键词：grain size severe dwarf TaVIP1 TavWA1 WHEAT

Effect of Nursing Interventions Based on APACHE II Scores on Gastrointestinal Function Recovery Time in Patients with Severe Pancreatitis: 《Journal of Clinical and Nursing Research》2025年第1期273-278,共6页Yinfeng Wu; Objective: To explore the application effect of nursing interventions based on APACHE II scores in patients with severe pancreatitis and its impact on the recovery time of the gastrointestinal function. Methods: A tot...; 关键词：Severe pancreatitis APACHE II score NURSING Gastrointestinal function

Effect of Ultra-Early Hemoperfusion on Emergency Treatment Outcomes in Patients with Severe Organophosphate Pesticide Poisoning: 《Journal of Clinical and Nursing Research》2025年第1期218-224,共7页Jianyu Yang; Objective: To analyze the emergency treatment effect of ultra-early hemoperfusion (HP) in patients with severe organophosphate pesticide poisoning (SOPP). Methods: Sixty SOPP patients treated in the emergency departme...; 关键词：Ultra-early hemoperfusion Severe organophosphate pesticide poisoning Emergency treatment outcomes

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