Current treatment for hepatitis C virus/human immunodeficiency virus coinfection in adults  

作　　者：Ratchapong Laiwatthanapaisan Apichet Sirinawasatien 

机构地区：[1]Gastroenterology Center,Vibhavadi Hospital,Bangkok 10900,Thailand [2]Department of Internal Medicine,Division of Gastroenterology,Rajavithi Hospital,College of Medicine,Rangsit University,Bangkok 10400,Thailand

出　　处：《World Journal of Clinical Cases》2021年第18期4491-4499,共9页世界临床病例杂志

摘　　要：Hepatitis C virus(HCV)/human immunodeficiency virus(HIV)coinfection is a major problem among HIV-infected patients,resulting in increased morbidity and mortality rates due to the acceleration of liver fibrosis progression by HIV,leading to liver cirrhosis and hepatocellular carcinoma.Although the efficacy of directacting antiviral therapy in patients with HIV/HCV coinfection and HCV monoinfection are similar in terms of sustained virologic response rate,there are some additional complications that arise in the treatment of patients with HIV/HCV coinfection,including drug-drug interactions and HCV reinfection due to the high risk behavior of these patients.This review will summarize the current management of HIV/HCV coinfection.

关 键 词：Viral hepatitis C Human immunodeficiency virus Liver fibrosis CIRRHOSIS Hepatocellular carcinoma Direct-acting antiviral agents Antiretroviral therapy 

分 类 号：R512.63[医药卫生—内科学] R512.91[医药卫生—临床医学]