Meigs’syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions:A case report  

作　　者：Xiao-Juan Wu Hang-Biao Xia Bao-Lin Jia Gao-Wu Yan Wen Luo Yong Zhao Xiao-Bin Luo 

机构地区：[1]Department of Respiratory and Critical Care Medicine,Suining Central Hospital,Suining 629000,Sichuan Province,China [2]Department of Oral and Maxillofacial Surgery,Suining Central Hospital,Suining 629000,Sichuan Province,China [3]Department of Radiology,Suining Central Hospital,Suining 629000,Sichuan Province,China

出　　处：《World Journal of Clinical Cases》2021年第18期4734-4740,共7页世界临床病例杂志

基　　金：Supported by the Scientific Research Project of Sichuan Provincial Health and Family Planning Commission,No.18PJ409.

摘　　要：BACKGROUND Meigs’syndrome is regarded as a benign ovarian tumor accompanied by pleural effusion and ascites,both of which resolve after removal of the tumor.Patients often seek treatment in the Department of Respiratory and Critical Care Medicine or other internal medicine departments due to symptoms caused by ascites or hydrothorax.Here,we report a rare case of Meigs'syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions.CASE SUMMARY A 52-year-old women was admitted to the Department of Respiratory and Critical Care Medicine due to coughing and expectoration accompanied with shortness of breath.Chest X-ray and chest computed tomography showed a modest volume of pleural fluid with pleural thickening in the right lung.The carbohydrate antigen 125(CA125)concentration was 150.8 U/mL(normal,0-35 U/mL)and no tumor cells were observed in pleural fluid.Nodules and a neoplasm with a fish meat-like appearance in the parietal pleura and nodules with a‘string of beads’-like appearance in the diaphragm were found by thoracoscopic examination.Furthermore,pelvic magnetic resonance revealed a pelvic mass measuring about 11.6 cm×10.0 cm×12.4 cm with heterogeneous signal intensity and multiple hypointense separations.Total abdominal hysterectomy,bilateral adnexectomy,and separation of pelvic adhesion were performed under general anesthesia.The pathology results showed granulosa cell tumor.At the 2-mo follow-up after the surgery,the hydrothorax subsided,and the CA125 level returned to normal.CONCLUSION For postmenopausal women with unexplained hydrothorax and elevated CA125,in addition to being suspected of having gynecological malignancy,Meigs’syndrome should be considered.

关 键 词：Meigs’syndrome Granulosa cell tumor HYDROTHORAX ASCITES Carbohydrate antigen 125 Case report 

分 类 号：R737.31[医药卫生—肿瘤]