Splenic Kaposi’s sarcoma in a human immunodeficiency virusnegative patient:A case report  

作　　者：Chuan-Jie Zhao Guang-Zhen Ma Yan-Jun Wang Jin-Hong Wang 

机构地区：[1]Department of Hepatobiliary Surgery,Liaocheng Second People’s Hospital,Linqing 252600,Shandong Province,China [2]Department of Pathology,Liaocheng Second People’s Hospital,Linqing 252600,Shandong Province,China [3]Department of Medical Oncology,Liaocheng Second People’s Hospital,Linqing 252600,Shandong Province,China [4]College of Life Science,Shaanxi Normal University,Xi'an 710119,Shaanxi Province,China

出　　处：《World Journal of Clinical Cases》2021年第18期4765-4771,共7页世界临床病例杂志

摘　　要：BACKGROUND Kaposi’s sarcoma(KS)is a malignancy that usually affects the skin of the lower extremities,and may involve internal organs.It originates from the vascular endothelium.It is well known that the development of KS is associated with human herpes virus 8(i.e.HHV8)infections.Sporadic KS cases have mainly been found in Africa.Isolated splenic KS in Asia has rarely been reported.We present here a case of KS primarily involving the spleen in a human immunodeficiency virus(HIV)-negative Chinese patient.CASE SUMMARY A 50-year-old male patient was admitted to hospital due to abdominal distension and discomfort,reduced food intake and weight loss.Medical examination revealed that the patient had moderate anemia,a low platelet count,slight fatty liver and a huge mass in the spleen.Spleen lymphoma was considered.An anti-HIV test was negative.The whole spleen was surgically excised.The final pathological diagnosis was nodular stage spleen KS,and the patient underwent total splenectomy.He recovered well and was discharged from hospital 12 d after surgery.Two weeks later,the patient developed liver metastasis and died within 1 mo after surgery.CONCLUSION KS is difficult to diagnose and pathological examination is necessary.KS has a poor prognosis and should be diagnosed and treated early to improve survival.

关 键 词：Kaposi’s sarcoma SPLEEN SPLENECTOMY Human immunodeficiency virus negative Human herpes virus 8 Case report 

分 类 号：R733.2[医药卫生—肿瘤]