Mucosal lesions of the upper gastrointestinal tract in patients with ulcerative colitis:A review  

作　　者：Yan Sun Zhe Zhang Chang-Qing Zheng Li-Xuan Sang 

机构地区：[1]Department of Gastroenterology,Shengjing Hospital of China Medical University,Shenyang 110022,Liaoning Province,China

出　　处：《World Journal of Gastroenterology》2021年第22期2963-2978,共16页世界胃肠病学杂志（英文版）

摘　　要：Ulcerative colitis(UC)is a chronic,nonspecific,relapsing inflammatory bowel disease.The colorectum is considered the chief target organ of UC,whereas upper gastrointestinal(UGI)tract manifestations are infrequent.Recently,emerging evidence has suggested that UC presents complications in esophageal,stomachic,and duodenal mucosal injuries.However,UC-related UGI tract manifestations are varied and frequently silenced or concealed.Moreover,the endoscopic and microscopic characteristics of UGI tract complicated with UC are nonspecific.Therefore,UGI involvement may be ignored by many clinicians.In addition,no standard criteria have been established for patients with UC who should undergo fibrogastroduodenoscopy.Furthermore,specific treatment recommendations may be needed for patients with UC-associated UGI lesions.Herein,we review the esophageal,gastric,and duodenal mucosal lesions of the UC-associated UGI tract,as well as the potential pathogenesis and therapy.

关 键 词：Ulcerative colitis Upper gastrointestinal tract Inflammatory bowel disease Endoscopic and microscopic manifestations 

分 类 号：R574.62[医药卫生—消化系统]