从中医药证关系论全国名中医朴炳奎治疗大肠癌中药性味归经特点  

Analyzing the Natures,Flavors and Meridian Tropisms of Chinese Herbs Used by PIAO Bingkui in Treating Colorectal Cancer Based on Drug-Syndrome Relationship of TCM

作　　者：陈欣 张海山 王立雅 朴炳奎[1] 郑红刚[1] CHEN Xin;ZHANG Haishan;WANG Liya;PIAO Bingkui;ZHENG Honggang(Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Anqing Municipal Hospital,Anqing 246000,China)

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]安庆市立医院,安徽安庆246000

出　　处：《中医药学报》2021年第6期68-71,共4页Acta Chinese Medicine and Pharmacology

基　　金：国家自然科学基金青年基金项目(81904196);中华中医药学会青年人才托举工程项目(QNRC1-03);北京自然科学基金面上项目(7172186);京津冀名老中医药专家朴炳奎学术传承推广项目(GZYGCS2018071)。

摘　　要：本文通过整理全国名中医朴炳奎教授治疗大肠癌的门诊病历,建立信息数据库,运用网络分析数据,总结出朴炳奎教授在治疗大肠癌辨证论治中,大肠癌主要呈现脾肾亏虚、湿热互结、痰瘀互结等7种证型。因证施用不同组方药物,其核心药物包括白术、山药、枳壳、益智仁。结合阴阳、脏腑理论和四气、五味、归经原理,揭示朴炳奎教授使用药物性味多为"温微、温平"性和"甘、苦、辛"味,归经多为"脾、胃、肺"经,阐明朴炳奎教授在治疗大肠癌过程中因证施药的规律。This study collected the outpatient medical records of colorectal cancer treated by professor PIAO Bingkui and established the information database for data analysis.It found that there were seven major patterns of colorectal cancer,such as deficiency of Spleen and Kidney,accumulation of damp-heat,as well as accumulation of phlegm and blood stasis.Key herbs used were Baizhu(Rhizoma Atractylodis Macrocephalae),Shanyao(Dioscorea opposita),Zhiqiao(Fructus aurantii)prepared with bran and Yizhiren(Fructus alpiniae oxyphyllae)prepared with salt.It discovered the medication rule based on syndrome differentiation in the treatment of colorectal cancer by professor PIAO,the herbs used were mainly with warm or mild feature and sweet,bitter or pungent flavour,which mainly went into the meridians of Spleen,Stomach and Lung.

关 键 词：大肠癌 四气五味 归经 朴炳奎 辨证立法 

分 类 号：R273[医药卫生—中西医结合]