卒中后认知损害的预测因素  

Predictors of post-stroke cognitive impairment

作　　者：刘欢[1] 陈莉[1] 陈晓虹 邢晓娜 Liu Huan;Chen Li;Chen Xiaohong;Xing Xiaona(Department of Neurology,People's Hospital of China Medical University,Shenyang 110016,China;Department of Neurology,Jinqiu Hospital of Liaoning Province,Shenyang 110016,China;Department of Neurology,Luohu District People's Hospital,the Third Affiliated Hospital of Shenzhen University,Shenzhen 518001,China)

机构地区：[1]中国医科大学人民医院神经内科,沈阳110016 [2]辽宁省金秋医院神经内科,沈阳110016 [3]深圳大学第三附属医院,深圳市罗湖区人民医院神经内科,深圳518001

出　　处：《国际脑血管病杂志》2021年第4期298-302,共5页International Journal of Cerebrovascular Diseases

基　　金：辽宁省科学技术计划项目(2019-MS-200,20180550394)。

摘　　要：卒中后认知损害(post-stroke cognitive impairment,PSCI)是指卒中后发生的认知功能下降,包括轻度认知损害和痴呆。预防PSCI至关重要,寻找预测因素是一个值得探索的方向。文章对PSCI预测因素的研究进展进行综述,包括人口统计学特征、卒中发病时的影像学特征、卒中本身特征以及分子标记物等,期望借此帮助筛选高危患者,及时干预以延缓PSCI的发生和发展。Post-stroke cognitive impairment(PSCI)refers to the decline of cognitive function after stroke,including mild cognitive impairment and dementia.It is very important to prevent PSCI,and it is a direction worth exploring to find the predictors.This article reviews the research progress of the predictors of PSCI,including demographic characteristics,imaging characteristics of stroke onset,stroke itself characteristics,and molecular markers,hoping to help screen high-risk patients and intervene in time to delay the occurrence and development of PSCI.

关 键 词：卒中 认知障碍 脑小血管疾病 危险因素 生物标志物 

分 类 号：R743.3[医药卫生—神经病学与精神病学]