老年多发性脑梗死并发肺炎的危险因素分析  

Risk Factors of Multiple Cerebral Infarction Complicated with Pneumonia in the Elderly

作　　者：王乐[1] 王柳毅[1] 师强 WANG Le;WANG Liu-yi;SHI Qiang(Department of Neurologic Medicine,Affiliated Hospital of Yanan University,Shaanxi 716000)

机构地区：[1]延安大学附属医院神经内科,陕西延安716000

出　　处：《医学临床研究》2021年第5期664-666,共3页Journal of Clinical Research

基　　金：陕西省教育厅青年项目(19JK0972)。

摘　　要：【目的】探讨老年多发性脑梗死合并肺炎的相关危险因素。【方法】选取本院收治的45例老年多发性脑梗死合并肺炎患者为观察组,另选取45例老年多发性脑梗死未合并肺炎患者作为对照组。观察比较两组患者基础资料、炎症指标、凝血功能及血小板参数,分析老年多发性脑梗死合并肺炎的相关危险因素。【结果】观察组患者年龄、梗死灶数目、肺部疾病病史比例、NIHSS评分均高于对照组,且差异有显著性(P<0.05)。观察组患者超敏C反应蛋白(hs-CRP)、白细胞介素-18(11,18)、淀粉样蛋白A(SSA)、降钙素原水平均高于对照组(P<0.05),两组血脂水平相比较差异无显著性(P>0.05)。观察组患者血小板分布宽度(PDW)高于对照组,血小板比容(PCT)、血小板计数(PLT)低于对照组(P<0.05),两组凝血功能指标相比较差异无显著性(P>0.05)。多因素分析显示,血小板参数、炎症指标、高龄、NIHSS评分是老年多发性脑梗死合并肺炎的相关因素(P<0.05)。【结论】老年多发性脑梗死合并肺炎患者年龄偏大,神经功能缺损严重,且存在炎症反应水平增高及血小板异常,应引起临床重视。【Objective】To investigate the risk factors with multiple cerebral infarction complicated with pneumonia in the elderly patients.[Methods]Forty-five elderly patients with multiple cerebral infarction complicated with pneumonia were enrolled in our hospital as the observation group,and 45 elderly patients with multiple cerebral infarction without pneumonia were selected as the control group.The basic clinical data,inflammation index,coagulation function and platelet parameters of the two groups were observed,and the related factors of multiple cerebral infarction complicated with pneumonia were analyzed.【Results】The age,number of infarctions,proportion of history of lung disease,and NIHSS scores in the observation group were higher than those in the control group(P<0.05).The levels of HS-CRP,IL-18,procalcitonin and SSA in the observation group were significantly higher than those in the control group(P<0.05).There was no significant difference in serum lipid levels between the two groups(P>0.05).The PDW(platelet distribution width)of the observation group was higher than that of the control group,while PCT and PLT were lower than those of the control group(P<0.05).There was no significant difference in coagulation function between the two groups(P>0.05).Multivariate analysis showed that platelet parameters,inflammatory markers,advanced age,and NIHSS scores were associated with pneumonia in the elderly patients with multiple cerebral infarction(P<0.05).[Conclusion]The elderly patients with multiple cerebral infarction complicated with pneumonia who are in aged,severe neurological deficits,high level of inflammatory response and platelet abnormalities need to be paid special attention clinically.

关 键 词：脑梗死/并发症 肺炎/并发症 危险因素 老年人 

分 类 号：R743.33[医药卫生—神经病学与精神病学]