机构地区:[1]甘肃中医药大学,兰州730020 [2]纽约大学 [3]甘肃省肿瘤医院
出 处:《实用肿瘤学杂志》2021年第3期207-211,共5页Practical Oncology Journal
基 金:甘肃省卫健委卫生健康管理项目(编号:31340301);甘肃省万名医师支援农村卫生工程项目(编号:31330101)。
摘 要:目的分析甘肃省肿瘤登记地区2009—2015年子宫体癌发病和死亡流行状况及变化趋势,为甘肃省子宫体癌的防治提供依据。方法审核整理2009—2015年甘肃省肿瘤登记地区子宫体癌发病(死亡)率、构成比、中国人口标化率(中标率)和世界人口标化率(世标率)等,分析年龄别发病及死亡情况,并通过Joinpoint回归模型计算年度变化百分比(Annual percentage change,APC)进行时间趋势分析。结果2009—2015年甘肃省肿瘤登记地区子宫体癌发病率为23.57/10万,中标率为19.86/10万;城市地区发病率23.18/10万,中标率19.27/10万;农村地区发病率26.00/10万,中标率23.15/10万,农村地区发病率高于城市地区;甘肃省2009—2015年肿瘤登记地区子宫体癌死亡率为14.61/10万,中标率12.14/10万;城市地区死亡率12.33/10万,中标率10.20/10万;农村地区死亡率12.08/10万,中标率10.97/10万,农村地区死亡率高于城市地区;年龄别发病率在0~20岁处于较低水平,35-岁年龄组迅速升高,60-岁年龄组达到高峰(82.26/10万);年龄别死亡率0~30岁处于较低水平,35-岁年龄组逐步升高,60-岁年龄组达到高峰(7.81/10万);甘肃省肿瘤登记地区2009—2015年子宫体癌发病率呈现下降趋势(APC=-4.9%,P=0.6),死亡率总体呈下降趋势(APC=-1.1%,P=0.3),但差异均无统计学意义。结论2009—2015年甘肃省子宫体癌发病率和死亡率呈现下降趋势,城市地区60岁以上女性是子宫体癌防控的重点对象。Objective The objective of this study was to analyze the trends of incidence and mortality of corpus uteri cancer in corpus uteri cancer.The reference data for evaluating prevention effects were provided.Methods Cases diagnosed as corpus uteri cancer from 2009 to 2015 in Gansu were extracted from the population-based database of Gansu cancer registry system and death registry system.Incidence,mortality,age-standardized rate(ASR)of China population,ASR of Segi′s world population and annual percentage change(APC)of corpus uteri cancer were calculated.Results From 2009 to 2015,the incidence rate of corpus uteri cancer was 23.57/100000.ASR China was 19.86/100000.The incidence rate in urban area was 23.18/100000,ASR China was 19.27/100000.The incidence in rural area was 26.00/100000,ASR China was 23.15/100000.From 2009 to 2015,mortality of corpus uteri cancer was 14.61/100000.The mortality rate of ASR China was 12.14/100000.The mortality in urban area was 12.33/100000,ASR China was 10.20/100000.The mortality in rural area was 12.08/100000.The mortality rate of ASR China was 10.97/100000.The age-specific incidence was at low level at 0~24 years of age,and rapidly increased after 35 years of age,then to be the maximum at 60 years of age(82.26/100000).The age-specific mortality was at low level at 0~24 years of age,and rapidly increased after 35 years of age,then to be the maximum at 60 years of age(7.81/100000).From 2009 to 2015,the incidence rate of ASR China of corpus uteri cancer in Gansu province showed a downward trend(APC=-4.9%,P=0.6).The mortality rate of ASR China of corpus uteri cancer in Gansu province showed a downward trend(APC=-1.1%,P=0.5).There was no statistically difference in the trend of change.Conclusion From 2009 to 2015,the incidence and mortality of corpus uteri cancer in Gansu increased show a downward trend.The female over 60 years old are the key objects of corpus uteri cancer prevention and control.
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