药物涂层球囊联合斑块旋切术治疗股浅动脉支架内再闭塞  

Drug-coated balloon angioplasty combined with directional atherectomy for the treatment of superficial femoral artery in-stent re-occlusion

作　　者：吴斐[1] 曾倩 崔文军[1] 王兵[1] WU Fei;ZENG Qian;CUI Wenjun;WANG Bing(Department of Vascular Surgery,Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan Province 450052,China)

机构地区：[1]郑州大学第五附属医院血管外科,450052

出　　处：《介入放射学杂志》2021年第5期508-511,共4页Journal of Interventional Radiology

基　　金：河南省医学科技攻关计划联合共建项目(2018020242)。

摘　　要：目的评价药物涂层球囊(DCB)联合TurboHawk定向斑块旋切术(DA)治疗股浅动脉支架内再闭塞的近中期效果。方法回顾性分析2016年8月至2018年8月在郑州大学第五附属医院接受血管内治疗的36例股浅动脉支架内再闭塞患者临床资料。其中19例接受DCB联合DA治疗,17例接受普通球囊血管成形术(POBA)联合DA治疗。对比两组近中期临床疗效。结果两组患者手术均获成功,平均随访(11.28±1.63)(9~15)个月。DCB+DA组术后6个月靶血管一期通畅率与POBA+DA组差异无统计学意义[94.7%(18/19)对82.4%(14/17),P>0.05],术后12个月一期通畅率高于POBA+DA组[89.5%(17/19)对64.7%(11/17),P=0.029]。两组患者术后6个月最小管腔直径(MLD)差异无统计学意义(P>0.05)。术后12个月DCB+DA组患者MLD显著高于POBA+DA组(P=0.029),远期管腔丢失(LLL)显著低于POBA+DA组(P=0.018)。结论DCB联合DA治疗股浅动脉支架内再闭塞具有较好的近中期效果。Objective To evaluate the short-term and mid-term curative effect of drug-coated balloon(DCB) angioplasty combined with TurboHawk directional atherectomy(DA) in treating superficial femoral artery in-stent re-occlusion. Methods The clinical data of 36 patients with superficial femoral artery in-stent re-occlusion, who were admitted to the Fifth Affiliated Hospital of Zhengzhou University of China during the period from August 2016 to August 2018 to receive endovascular therapy, were retrospectively analyzed. Of the 36 patients, DCB angioplasty combined with DA was employed in 19(DCB+DA group) and plain old balloon angioplasty(POBA) was adopted in 17(POBA+DA group). The short-term and mid-term curative effect was compared between the two groups. Results Successful procedure was accomplished in all patients of both groups. The mean follow-up time was(11.28±1.63) months(9-15 months). The postoperative 6-month primary patency rate of target vessels in DCB+DA group and POBA+DA group was 94.7%(18/19) and 82.4%(14/17)respectively, the difference between the two groups was not statistically significant(P>0.05). The postoperative12-month primary patency rate of target vessels in DCB+DA group was 89.5%(17/19), which was significantly higher than 64.7%(11/17) in POBA+DA group(P=0.029). The difference in the postoperative 6-month minimum lumen diameter(MLD) between the two groups was not statistically significant(P>0.05). In DCB+DA group,the postoperative 12-month MLD was obviously larger than that in POBA +DA group(P=0.029), while the long-term lumen loss(LLL) was strikingly less than that in POBA+DA group(P=0.018). Conclusion For the treatment of superficial femoral artery in-stent re-occlusion, DCB+DA has satisfactory short-term and mid-term curative effect.(J Intervent Radiol, 2021, 30: 508-511)

关 键 词：股浅动脉 支架内再闭塞 药物涂层球囊 

分 类 号：R743.1[医药卫生—神经病学与精神病学]