儿童脑回状皮脂腺痣14例临床分析  

Clinical analysis of 14 children with cerebriform sebaceous nevus

作　　者：韩晓锋[1] 孙娟[1] 徐教生[1] 马琳[1] Han Xiaofeng;Sun Juan;Xu Jiaosheng;Ma Lin(Department of Dermatology,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China)

机构地区：[1]首都医科大学附属北京儿童医院皮肤科,100045

出　　处：《中华皮肤科杂志》2021年第6期529-531,共3页Chinese Journal of Dermatology

基　　金：北京市医院管理中心儿科学科协同发展中心专项(XTZD20180502)。

摘　　要：目的探讨脑回状皮脂腺痣的临床表现、病理特征及手术时机。方法回顾2014年6月至2019年12月北京儿童医院皮肤科诊治的14例脑回状皮脂腺痣患儿的临床特点、组织病理学特征以及手术治疗时机。结果14例患儿中男10例,女4例,出生即有皮损,单发且位于头面部,外观与脑回结构相似,平均直径4.79 cm。所有患儿系统检查均无异常。组织病理:具有明显宽大的乳头瘤样增生,伴增生的皮脂腺及不成熟的毛囊。14例患儿均行手术治疗,平均手术年龄1.94岁。术后随访半年至6年,均无复发。结论脑回状皮脂腺痣具有独特的脑回状外观,多位于头面部,易引起重视从而选择更早进行手术治疗。Objective To investigate clinical manifestations and histopathological features of and surgical timing for cerebriform sebaceous nevus.Methods Clinical data were collected from 14 children with cerebriform sebaceous nevus in Beijing Children′s Hospital from June 2014 to December 2019,and clinical manifestations,histopathological features and surgical timing were analyzed retrospectively.Results Of the 14 children,10 were males and 4 were females.They presented with skin lesions at birth,which were solitary and located on the head and face.These skin lesions gave a cerebriform appearance,with an average diameter of 4.79 cm.Systemic examination showed no abnormality in any children.Histopathological examination showed obvious papillomatous epidermal hyperplasia,large number of mature sebaceous glands and immature hair follicles.All the 14 children underwent surgeries at an average age of 1.94 years.No recurrence was observed during the follow?up of 6 months to 6 years after surgery.Conclusions Cerebriform sebaceous nevus is characterized by a unique cerebriform appearance,mostly occurs on the head and face,and is liable to attract attention,which usually leads to an earlier surgical selection.

关 键 词：皮脂腺肿瘤 脑回状皮脂腺痣 儿童 

分 类 号：R739.5[医药卫生—肿瘤]