Concise Total Syntheses of Bioactive Alkaloids Enabled by Development or Application of Cascade Reactions:A Personnel Adventure  

作　　者：Xingang Xie Xuegong She 

机构地区：[1]State Key laboratory of Applied Organic Chemistry,College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou,Gansu,730000 China

出　　处：《Chinese Journal of Chemistry》2021年第4期795-801,共7页中国化学（英文版）

基　　金：National Natural Science Foundation of China(Nos.21125207,21572088 and 21871118).

摘　　要：Design and development of new tactics and strategies to improve synthetic efficiency is a hot topic and main concern in nowadays’chemical synthesis of bioactive natural products.Cascade reactions,which construct several bonds in one step via an orchestrated sequence,have been regarded as an important tactic to rapidly increase the molecular complexity,therefor to improve the synthetic efficiency.In this perspective account,we demonstrated and highlighted the significance of cascade reaction developments and applications in concise syntheses of bioactive alkaloids based on our own recent adventure in this research field.

关 键 词：Natural products ALKALOIDS Total synthesis Cascade reactions 

分 类 号：O62[理学—有机化学]