Insights for integrative medicinal potentials of Ethiopian Kale(Brassica carinata): Investigation of antibacterial, antioxidant potential and phytocompounds composition of its leaves  

作　　者：Kamaraj Murugesan Kidist Mulugeta Eyosias Hailu Worku Tamene Sangilimuthu Alagar Yadav 

机构地区：[1]Department of Biotechnology,College of Biological and Chemical Engineering,Addis Ababa Science and Technology University,Addis Ababa 16417,Ethiopia [2]Department of Biotechnology,School of Life Sciences,Karpagam Academy of Higher Education,Coimbatore,Tamil Nadu 641021,India

出　　处：《Chinese Herbal Medicines》2021年第2期250-254,共5页中草药（英文版）

基　　金：Addis Ababa Science and Technology University, Ethiopia for providing partial financial support (Grant Reference No-AASTU-SSRF-CBCE-BT-2018)。

摘　　要：Objective:To compare the phytochemical and antimicrobial activity of Ethiopian Kale leaves infusions,investigate the antioxidant activity and profile the major phytochemicals existing in the better solvent system.Methods:Ethiopian Kale leaves were collected from Addis Ababa,Ethiopia,and extracted using different solvents.The qualitative phytochemical analysis,antibacterial assays,and Fourier Transform Infrared(FTIR) analysis are executed for all extracts.Antioxidant assay and Gas Chromatography-Mass Spectrometry(GC-MS) analysis are carried out for the solvent system,which showed better activity in preliminary studies.Results:The qualitative phytochemical analysis exposed the presence of different classes of phytoconstituents in most of the tested extracts.The broad spectrum of antibacterial activity(7-15 mm) was noted against the tested bacterial species.The functional groups of the extracts are reported by FTIR analysis.The antioxidant ability of ethanol extract was found to be(62.92±0.34)% for 2,2-diphenyl-1-picrylhydrazyl(DPPH*) assay and(71.12±0.41)% for 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS) assay.More than 17 major phytocompounds in ethanol extract were profiled by GC-MS analysis.Conclusion:The ethanol extract of Ethiopian Kale leaves contain a good source of phytochemicals and it can be a significant source for various functional applications.

关 键 词：antagonistic activity antioxidant functional groups GC–MS analysis leaf extract THERAPEUTICS 

分 类 号：R284.1[医药卫生—中药学]