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作 者:梁靓[1] 吴郁[1] 杨蕊[1] 李蓉[1] Liang Liang;Wu Yu;Yang Rui;Li Rong(Reproductive Medical Center,Peking University Third Hospital,Beijing 100191,China)
出 处:《中华生殖与避孕杂志》2021年第4期367-371,共5页Chinese Journal of Reproduction and Contraception
基 金:国家杰出青年科学基金(81925013)。
摘 要:卵巢交界性肿瘤(borderline ovarian tumors,BOTs)是一种生物学行为介于卵巢良、恶性肿瘤之间的特殊类型,好发于生育年龄女性,预后较好,合并不孕率较高,BOTs患者行保留生育功能手术可行,早期、无组织学高危因素的BOTs术后行辅助生殖技术(assisted reproductive technology,ART)治疗可行,生育咨询应成为BOTs临床管理的一个组成部分,对BOTs术后不孕症或不孕高危因素患者应尽早向生殖医生寻求合适的助孕治疗。本文围绕BOTs与保留生育功能手术及ART的安全性展开综述。Borderline ovarian tumors(BOTs)are characterized by the histopathologic feature and biologic behavior which intermediate between clearly benign and frankly malignant ovarian tumors.BOTs are more common in younger women,and most patients are diagnosed in the early stage and with infertility.Fertility sparing surgery(FSS)is safety and beneficial for women with BOTs who desire to maintain their fertility.Assisted reproductive technology is safety and beneficial for women with BOTs in early stage and without any histological high-risk criterion.Fertility counselling should become an integral part of the clinical management of women with BOTs.For BOTs patients with infertility or high risk factors of infertility after FSS operation,it is necessary to seek appropriate treatment from reproductive doctors as early as possible.This article reviews the safety of BOTs,fertility sparing surgery and assisted reproductive treatment.
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