14例小汗腺螺旋腺瘤临床及病理特征分析  

Analysis of clinical and pathological features of 14 patients with eccrine spiradenoma

作　　者：徐斐妮 陈爱军[1] XU Feini;CHEN Aijun(Department of Dermatology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆医科大学附属第一医院皮肤科,重庆400016

出　　处：《中国麻风皮肤病杂志》2021年第7期424-427,共4页China Journal of Leprosy and Skin Diseases

基　　金：国家自然科学基金(编号:81874238)。

摘　　要：回顾性分析2015-2019年我院皮肤科确诊为小汗腺螺旋腺瘤的14例患者的临床及病理资料,并复习相关文献。结果示14例小汗腺螺旋腺瘤患者中,男5例,女9例,中位发病年龄为40.5岁。10例患者皮疹发生于躯干。皮损形态为皮色、红色、蓝色、浅褐色的皮下包块或结节,且多伴疼痛。14例患者临床首诊均误诊,误诊为表皮囊肿6例、色素痣3例、皮肤纤维瘤2例、皮下结节2例、平滑肌瘤1例。组织病理学特征为界清且外覆包膜的肿瘤团块,伴导管分化,可见核圆深染及较大淡染的两种肿瘤细胞,部分病例见血管扩张。免疫组化提示CEA局灶(+)、EMA局灶(+),S-100(+)、SMA(+)。The clinical and histopathology data of 14 cases with eccrine spiradenoma in our hospital from 2015 to 2019 were analyzed retrospectively,and the relevant literature were reviewed.Fourteen patients were collected including 5 males and 9 females with the median age at onset of 40.5.The lesions were on the trunk in 10 patients.The manifestations of lesions were subcutaneous masses or nodules with skin color,red,blue and light brown,and most of them were accompanied by pain.All the patients were misdiagnosed at the first visit,6 as epidermal cyst,3 as pigmented nevus,2 as dermatofibroma,2 as subcutaneous nodules and one as leiomyoma.Histological sections showed the masses were surrounded by a delicate fibrous capsule with ductal differentiation,and two types of atypical cells with nuclear round hyperchromatic or large pale and vascular dilatation were seen.Immunohistochemistry showed CEA focal(+),EMA focal(+),S-100(+),SMA(+).

关 键 词：小汗腺螺旋腺瘤 病理 免疫组化 

分 类 号：R739.5[医药卫生—肿瘤]