火炭母提取物抑菌性能研究  

Study on Antimicrobial Properties of the Extracts from Polygonum chinense L.

作　　者：宋姗姗 杨艾华 王微微 王俣棋 范红结 王小敏 SONG Shan-shan;YANG Ai-hua;WANG Wei-wei(School of Basic Medicine Sciences,Zunyi Medical University,Zunyi,Guizhou 563000)

机构地区：[1]遵义医科大学基础医学院,贵州遵义563000

出　　处：《安徽农业科学》2021年第12期187-189,共3页Journal of Anhui Agricultural Sciences

基　　金：国家自然科学基金地区科学基金项目(31860706);贵州省科技计划项目(黔科合平台人才〔2018〕5772-005);贵州省教育厅青年科技人才成长项目(黔教合KY字〔2018〕222);遵义医学院博士科研启动资金项目(F-794);遵义医科大学大学生创新创业训练计划项目(ZYDC2019037)。

摘　　要：为解决细菌在不同食品表面以及食品工业环境中形成生物膜引起食品质量安全问题,以中药材火炭母提取物为对象,对不同供试菌株进行抑制细菌及抑制细菌生物膜试验,探讨其抑菌性能。结果表明:火炭母提取物对金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌和铜绿假单胞菌的生长均有一定的抑制作用,其最低抑菌浓度(MIC)分别为3.91、1.95、15.63、15.63 mg/mL;在亚抑菌浓度下,火炭母提取物能有效抑制金黄色葡萄球菌和表皮葡萄球菌生物膜形成,其最小生物膜清除浓度(MBEC)分别为0.98和0.49 mg/mL。In order to solve the problem of food quality and safety caused by bacteria forming biofilm on different food surfaces and in food industry environment,this study took the extract of Polygonum chinense as the object,carried out bacteriostatic and bacteriostatic membrane tests on different index strains,and discussed its bacteriostatic performance.The results showed that the extract of Polygonum chinense had a certain inhibitory effect on the growth of Staphylococcus aureus,Staphylococcus epidermidis,Escherichia coli and Pseudomonas aeruginosa,and the minimum inhibitory concentrations(MIC)was 3.91,1.95,15.63 and 15.63 mg/mL,respectively.Under the concentration of subbacteriostatic bacteria,the extract of Polygonum chinense could effectively inhibit the biofilm formation of Staphylococcus aureus and Staphylococcus epidermidis,the minimum biofilm removal concentration(MBEC)was 0.98 and 0.49 mg/mL,respectively.

关 键 词：火炭母 提取物 抑菌 细菌 生物膜 

分 类 号：R285[医药卫生—中药学]