早发型妊娠期肝内胆汁淤积症致亚急性肝衰竭:1例报道并文献复习  

Subacute hepatic failure caused by early-onset intrahepatic cholestasis of pregnancy: one case report and literature review

作　　者：刘晓琳[1] 李茂涓 谭英[1] 缪应雷[1] LIU Xiaolin;LI Maojuan;TAN Ying;MIAO Yinglei(Department of Gastroenterology,the First Affiliated Hospital of Kunming Medical University,Yunnan Institute of Digestive Disease,Kunming Engineering Research Center of Digestive Disease,Kunming 650032,China)

机构地区：[1]昆明医科大学第一附属医院消化内科、云南省消化疾病研究所、昆明市消化疾病诊治工程技术研究中心,云南昆明650032

出　　处：《胃肠病学和肝病学杂志》2021年第6期687-690,共4页Chinese Journal of Gastroenterology and Hepatology

基　　金：国家自然科学基金(U1802282,81660100,81670501,81960108);云南省运用基础研究项目[2019FE-001(036)];云南省卫计委医学领军人才(L-201607)。

摘　　要：妊娠期肝内胆汁淤积症(intrahepatic cholestasis of pregnancy,ICP)是妊娠中晚期特有的一种可逆性的胆汁淤积性肝病,对胎儿危害较大,但很少对母体有损害,鲜有病例报道母体出现肝衰竭表现。本例为昆明医科大学第一附属医院消化内科2016年收治的诊断为早发型ICP致亚急性肝衰竭患者,随访至今。现详细报道病例特点并回顾相关文献,为临床医师早期识别和诊疗早发型ICP患者提供参考。Intrahepatic cholestasis of pregnancy(ICP)is a reversible cholestatic liver disease specific to the middle and the third trimester of pregnancy.The disease is harmful to the fetus and rarely damages the mother.Few cases have been reported of hepatic failure in the mother.This patient was diagnosed as subacute hepatic failure due to early-onset ICP by the Department of Gastroenterology,the First Affiliated Hospital of Kunming Medical University in 2016,and has been followed up to date.The characteristic of this patient was reported in detail and relevant literature was reviewed to provide references for clinicians to identify and diagnose patient with early-onset ICP.

关 键 词：早发型妊娠期肝内胆汁淤积症 肝衰竭 诊断 治疗 

分 类 号：R575[医药卫生—消化系统]