皮肤平滑肌瘤43例临床及组织病理分析  

Clinicopathological analysis of 43 cases of cutaneous leiomyoma

作　　者：吴婷[1] 童咏花 张凌云[1] 吴士迪 黄长征[1] WU Ting;TONG Yong-hua;ZHANG Ling-yun;WU Shi-di;HUANG Chang-zheng(Department of Dermatology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院皮肤科,湖北武汉430022 [2]长江航运总医院皮肤科,湖北武汉430022

出　　处：《临床皮肤科杂志》2021年第6期331-334,共4页Journal of Clinical Dermatology

摘　　要：目的:探讨皮肤平滑肌瘤的临床及组织病理特点。方法:回顾性分析该科1989年6月-2019年6月经组织病理确诊的43例皮肤平滑肌瘤患者的临床及组织病理特征。结果:43例患者中男17例,女26例,其中25~60岁者最多见,占79.1%;病程>20年者8例(18.6%);皮损位于下肢者最多见;伴疼痛者21例(48.8%)。所有样本中毛发平滑肌瘤16例(37.2%),血管平滑肌瘤22例(51.2%),生殖器平滑肌瘤5例(11.6%),术前正确诊断率为25.6%。结论:皮肤平滑肌瘤常见于中青年女性,多发者常见于躯干,单发者常见于下肢,误诊率高,皮损组织病理检查是唯一确诊手段。多发性皮肤平滑肌瘤可作为诊断潜在恶性肿瘤的线索。Objective:To explore the clinicopathological features of cutaneous leiomyoma.Methods:The clinicopathological features of 43 cases of cutaneous leiomyomas confirmed by histopathology in the department from June 1989 to June 2019 were retrospectively analyzed.Results:Among the 43 patients,17 were male and 26 were female,mostly aged from 25 to 60 years(79.1%).Eight cases had a disease duration of more than 20 years.The most common affected sites were legs.Twenty-one patients(48.8%)were found to have pain.There were 16 cases of piloleiomyomas(37.2%)/22 cases of angioleiomyomas(51.2%),and 5 cases of genital leiomyomas(11.6%).The correct preoperative diagnosis rate was 25.6%.Conclusion:Cutaneous leiomyomas is more common in young and middle-aged female,with multiple lesions on the surface of trunk and solitary one on the lower extremities.Due to the high rate of misdiagnosis,biopsy is the only way to make correct diagnosis.Multiple cutaneous leiomyomas might be a clue for an underlying malignancy.

关 键 词：平滑肌瘤 皮肤 平滑肌瘤 毛发 平滑肌瘤 血管 平滑肌瘤 生殖器 组织病理分析 

分 类 号：R739.5[医药卫生—肿瘤]